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                        "paginaFinal" => "529"
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Letter to the Editor
From clots to cuts in antiphospholipid syndrome
De los coágulos a los cortes en el síndrome antifosfolípido
Abihai Lucas Hernándeza,
Autor para correspondencia
abihai.lucas@comunidad.unam.mx

Corresponding author.
, Yehuda Shoenfeldb,c
a Departamento de estudios de Posgrado, Universidad Nacional Autónoma de México (UNAM), Mexico City, Mexico
b Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Tel-Aviv, Israel
c Reichman University, Herzliya, Israel
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ISSN: 1699258X
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