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Letter to the Editor
Cytokine storm in Chikungunya: Correspondence
Tormenta de citoquinas en Chikungunya: Correspondencia
H. Daungsupawonga,
Autor para correspondencia
hinpetchdaung@gmail.com

Corresponding author.
, V. Wiwanitkitb
a Private Academic Consultant, Phonhong, Lao People's Democratic Republic
b Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, India
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We would like to share ideas on the publication &#8220;Cytokine storm in Chikungunya&#58; Can we call it multisystem inflammatory syndrome associated with Chikungunya&#63;&#8221;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a>&#46; This article presents two severe cases of multisystem involvement and similarities to Multisystem Inflammatory Syndrome in Children &#40;MIS-C&#41; associated with SARS-CoV-2 that resulted from Chikungunya &#40;CHIKV&#41; infection in Paraguay&#46; The patients&#8217; symptoms included myocarditis&#44; fever&#44; rash&#44; vomiting&#44; stomach pain&#44; and coronary artery abnormalities&#46; Both patients had good clinical responses after receiving treatment with methylprednisolone and intravenous immunoglobulin &#40;IVIG&#41;&#46; In the article&#44; it is questioned if this severe CHIKV infection-related symptom qualifies as a &#8220;multisystem inflammatory syndrome associated with Chikungunya&#46;&#8221;</p><p id="par0010" class="elsevierStylePara elsevierViewall">The absence of comprehensive data on the patients&#8217; demographics&#44; comorbidities&#44; and outcomes after the initial treatment response is one of the report&#39;s weak points&#46; It is difficult to completely comprehend the variables that might have influenced the severity of the CHIKV infection and the effectiveness of the given treatment in the absence of this information&#46; Furthermore&#44; the report skips over the underlying processes of the Chikungunya cytokine storm and how it can contribute to the multisystem involvement that develops in these cases&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">More thorough investigations into the pathophysiology of severe CHIKV infection and its similarities to MIS-C&#44; as well as the creation of uniform diagnostic standards and treatment guidelines&#44; may be among the future avenues for this field of study&#46; Effective collaboration among healthcare practitioners&#44; researchers&#44; and public health authorities can enhance comprehension and treatment of severe CHIKV patients involving several systems&#46; Preventing and lessening the effects of future epidemics also depend on ongoing surveillance and monitoring of CHIKV outbreaks and related complications&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Ethical approval</span><p id="par0020" class="elsevierStylePara elsevierViewall">For this type of study formal consent is not required&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Informed consent</span><p id="par0025" class="elsevierStylePara elsevierViewall">For this type of study consent for publication is not required&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Authors&#8217; contribution</span><p id="par0030" class="elsevierStylePara elsevierViewall">HP&#58; 50&#37; ideas&#44; writing&#44; analyzing&#44; approval&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">VW&#58; 50&#37; ideas&#44; supervision&#44; approval&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Funding</span><p id="par0040" class="elsevierStylePara elsevierViewall">This study was not supported by any funding</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conflict of interest</span><p id="par0045" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflict of interest&#46;</p></span></span>"
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Información del artículo
ISSN: 1699258X
Idioma original: Inglés
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2024 Agosto 12 2 14

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