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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We read with interest the article published by the Rheumatology Department of the Jos&#233; Mar&#237;a Cullen Hospital in Santa Fe&#44; Argentina&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">It seems relevant to compare the evolution of systemic lupus erythematosus &#40;SLE&#41; in a private and a public center&#44; since the outcome of this disease could be affected by various factors involved in being at any of these centers&#44; such as pharmacological treatment provided and the demographic characteristics of the patient attending a public or a private center&#46; These factors influence the quality of life and the degree of disease activity in a patient&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">However&#44; the study has some limitations that put into question the reported results&#46; First&#44; the time at which the authors started monitoring the patients is not defined&#46; This could bias the study because the survival prognosis of SLE varies according to several factors&#44; including the degree of disease activity of the patient&#44; the age and comorbidities at the time of diagnosis&#44; among others&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Second&#44; the study does not determine whether patients are exclusive users of the health system &#40;public or private&#41;&#44; if they have access to both health systems or if&#44; during the years of follow up&#44; they moved from one system to another&#46; This would lead to patients receiving more than one treatment simultaneously or different treatments in each center in different periods&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Finally&#44; the use of informed consent is important in a study&#44; as it ensures that the patient is aware and accepts to participate&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a> It is unusual to require informed consent in a retrospective study&#44; as the methods section says that it had not been sought&#44; but later mentions that it was indeed obtained&#44; which can cause confusion about the ethics of the study&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Finally&#44; we believe that some data could have been better explained&#44; both in tables and in text&#44; as it can confuse readers causing misinterpretation of the data&#46; For example&#44; in the results section&#44; the authors explain that&#44; given two groups of people&#44; both black&#44; one with health insurance and the other without health insurance increased mortality was observed in the group without health insurance&#44; which results in ethnicity not playing a decisive role in the survival of patients&#44; which may be debated&#44; since in this case&#44; the ethnicity was the same in all patients studied&#44; and not a variable&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a></p></span>"
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                            3 => "P&#46; Isaza Arenas"
                            4 => "A&#46; Gaviria G&#243;mez"
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Journal Information
Vol. 11. Issue 4.
Pages 260 (July - August 2015)
Vol. 11. Issue 4.
Pages 260 (July - August 2015)
Letter to the Editor
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Differences in Survival Between Patients With Systemic Lupus Erythematosus From a Public and a Private Center
Diferencias en supervivencia en pacientes con lupus eritematoso sistémico de un centro privado y uno público
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Maria Claudia Godoy Carrillo
Corresponding author
mclaudiag90@gmail.com

Corresponding author.
, Alejandra Meneses-Saco
Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru
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To the Editor:

We read with interest the article published by the Rheumatology Department of the José María Cullen Hospital in Santa Fe, Argentina.1

It seems relevant to compare the evolution of systemic lupus erythematosus (SLE) in a private and a public center, since the outcome of this disease could be affected by various factors involved in being at any of these centers, such as pharmacological treatment provided and the demographic characteristics of the patient attending a public or a private center. These factors influence the quality of life and the degree of disease activity in a patient.2

However, the study has some limitations that put into question the reported results. First, the time at which the authors started monitoring the patients is not defined. This could bias the study because the survival prognosis of SLE varies according to several factors, including the degree of disease activity of the patient, the age and comorbidities at the time of diagnosis, among others.3

Second, the study does not determine whether patients are exclusive users of the health system (public or private), if they have access to both health systems or if, during the years of follow up, they moved from one system to another. This would lead to patients receiving more than one treatment simultaneously or different treatments in each center in different periods.

Finally, the use of informed consent is important in a study, as it ensures that the patient is aware and accepts to participate.4 It is unusual to require informed consent in a retrospective study, as the methods section says that it had not been sought, but later mentions that it was indeed obtained, which can cause confusion about the ethics of the study.

Finally, we believe that some data could have been better explained, both in tables and in text, as it can confuse readers causing misinterpretation of the data. For example, in the results section, the authors explain that, given two groups of people, both black, one with health insurance and the other without health insurance increased mortality was observed in the group without health insurance, which results in ethnicity not playing a decisive role in the survival of patients, which may be debated, since in this case, the ethnicity was the same in all patients studied, and not a variable.5

Acknowledgement

We would like to thank Dr. Antonio Bernabé-Ortiz for his guidance in the preparation of this letter.

References
[1]
M.M. Schmid, S.G. Roverano, S.O. Paira.
Comparación de datos demográficos, presentación clínica, tratamiento y desenlace de pacientes con lupus eritematoso sistémico tratados en un centro público y otro privado de salud en Santa Fe, Argentina.
Reumatol Clin, 10 (2014), pp. 294-298
[2]
C.J. Velásquez Franco, J.J. Yépes Núñez, K. Ariza Mendoza, P. Isaza Arenas, A. Gaviria Gómez, C. Muñoz-Grajales, et al.
Estimación de la calidad de vida relacionada con la salud y medidas de utilidad en una población de pacientes colombianos con lupus eritematoso sistémico.
Rev Colomb Reumatol, 20 (2013), pp. 183-194
[3]
M. Schmid, S. Roverano, O. Paira.
Manifestaciones y evolución clínica de pacientes con LES en un hospital de referencia.
Rev Arg Reumatol, 24 (2013), pp. 28-32
[4]
R. Cañete, D. Guilhem, K. Brito.
Consentimiento informado: algunas consideraciones actuales.
Acta Bioethica, 18 (2012), pp. 121-127
[5]
J.D. Reveille, A. Bartolucci, G.S. Alarcón.
Prognosis in systemic lupus erythematosus. Negative impact of increasing age at onset, black race, and thrombocytopenia, as well as causes of death.
Arthritis Rheumatol, 33 (1990), pp. 39-47

Please cite this article as: Godoy Carrillo MC, Meneses-Saco A. Diferencias en supervivencia en pacientes con lupus eritematoso sistémico de un centro privado y uno público. Reumatol Clin. 2015;11:260

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