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"en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A, B) Deformity and swelling on the lateral face of the IPJ of the second, third and fourth fingers, with predominance on the right hand (arrows).</p>"
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"textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Clinical case</span><p id="par0005" class="elsevierStylePara elsevierViewall">A 14-year-old male, with no history of interest, consulting with a year's history of deformity and symmetrical pattern swelling on the lateral face of the proximal interphalangeal joints (IPJ) of the second, third and fourth fingers, with predominance in the right hand (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A and B). He reported no pain, limitation or other associated skin or systemic manifestations.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Analysis, which included complete blood count, biochemistry, coagulation, erythrocyte sedimentation rate, C reactive protein, HLA-B27, rheumatoid factor and antinuclear antibodies, was normal or negative. Plain X-ray showed an increase in soft tissue on the second, third and fourth IPJ of the right hand, with no signs of associated joint or bone involvement (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). Magnetic resonance imaging showed oedema and increased soft tissue on the second, third and fourth fingers of the right hand. There were no signs of synovitis or associated collections (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>). A skin biopsy was performed that revealed compact hyperkeratosis and thickening of the dermis, with an increase in the number of collagen fibres and fibroblasts.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">This led to a diagnosis of classical pachydermodactyly; given the benign nature of this entity and the absence of associated clinical symptoms a wait-and-see approach was decided. After 18 months of six-monthly follow-up in the paediatric dermatology and rheumatology clinic, the patient remains asymptomatic, without pain, functional limitation or other associated clinical manifestations.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Discussion</span><p id="par0020" class="elsevierStylePara elsevierViewall">Paquidermodactyly, initially described in 1973<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> and later in 1975,<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> is an acquired and under-diagnosed form of digital fibromatosis, of benign course and predominantly affects young males. It is characterised by the presence of progressive, asymptomatic and bilateral swelling of the IP joints of both hands.<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">1–3</span></a> The cause is unknown, although the possible implication of repeated micro trauma, genetic and hormonal factors has been postulated.<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">4,5</span></a> Diagnosis of this entity is essentially clinical, and must be differentiated from juvenile idiopathic arthritis, with characteristic clinical, analytical and radiological findings.<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">4–6</span></a> Clinical treatment measures are preferred, although intralesional glucocorticoids could be used, and surgery as an alternative in some subgroups of patients.<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">3–6</span></a></p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Ethical responsibilities</span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Protection of people and animals</span><p id="par0025" class="elsevierStylePara elsevierViewall">The authors declare that neither human nor animal testing has been carried out under this research.</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Data confidentiality</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare that they have complied with their work centre protocols for the publication of patient data.</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Right to privacy and informed consent</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors have obtained the informed consent of the patients and/or subjects referred to in the article. This document is held by the corresponding author.</p></span></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Conflict of interests</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors have no conflict of interest to declare.</p></span></span>"
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