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Vol. 20. Issue 1.
Pages 20-23 (January 2024)
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Vol. 20. Issue 1.
Pages 20-23 (January 2024)
Case Report
Termination of pregnancy in lupus nephritis: A bioethical analysis with the integrative method
Interrupción del embarazo en nefritis lúpica: un análisis bioético desde el método integral
Tábata Cano-Gámeza, Adriana Concepción Lobato-Belmontea, Ingris Peláez-Ballestasa, Gabriel Medrano-Ramíreza, Juan Carlos de León-Carbajalb, Amaranta Manrique de Laraa,
Corresponding author
a Servicio Reumatología, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico
b Servicio Medicina Materno Fetal, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico
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Table 1. Patient's evolution during hospitalisation.
Background and objective

Termination of pregnancy in patients with rheumatic diseases is controversial and a bioethical analysis is rarely performed. In this study we analysed the case of a pregnant patient with lupus nephritis unresponsive to treatment, for whom termination of pregnancy is considered.


The integrative model was applied combining different normative ethical theories.


From a utilitarian perspective, termination of pregnancy is justifiable, seeking the greatest benefit for the greatest number of stakeholders. Deontology justifies both terminating and continuing the pregnancy, focusing on the action itself and on autonomy. In virtue ethics the importance of decisions rests with the person who performs the action seeking flourishing; termination of pregnancy would be justifiable.

Discussion and conclusions

Interruption of pregnancy is a justifiable solution following the integrative model. Bioethical analysis of paradigmatic cases is essential to ensure the best possible action and as a precedent for future similar situations in rheumatology.

Termination of pregnancy
Lupus nephritis
Integrative method
Antecedentes y objetivo

La interrupción del embarazo en pacientes con enfermedades reumatológicas es controvertida y pocas veces se realiza un análisis bioético. En este estudio analizamos el caso de una paciente embarazada con nefritis lúpica sin respuesta a tratamiento en quien se plantea la interrupción del embarazo.


Se aplicó el modelo integral incluyendo distintos sistemas normativos para el análisis del dilema.


Desde el utilitarismo es justificable la interrupción del embarazo, buscando el mayor beneficio para la mayoría de las partes. La deontología justifica tanto continuar como interrumpir el embarazo, centrando la importancia en la acción misma y en la autonomía. Para la ética de la virtud la importancia de las decisiones recae en la persona que realiza la acción buscando el florecimiento; la interrupción del embarazo sería justificable.

Discusión y conclusiones

La interrupción del embarazo sería una solución adecuada según el modelo integral. El análisis bioético de casos paradigmáticos es fundamental para asegurar el mejor actuar posible en casos similares en Reumatología.

Palabras clave:
Interrupción del embarazo
Nefritis lúpica
Método integral


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