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Case Report
DOI: 10.1016/j.reumae.2018.09.003
Available online 5 October 2018
Tjalma Syndrome (Pseudo-pseudo Meigs’) as Initial Manifestation of Juvenile-onset Systemic Lupus Erythematosus
Síndrome de Tjalma (pseudo-pseudo Meigs) como manifestación inicial de lupus eritematoso sistémico de inicio juvenil
Alfonso Ragnar Torres Jiméneza,
Corresponding author

Corresponding author.
, Eunice Solís-Vallejoa, Adriana Ivonne Céspedes-Cruza, Maritza Zeferino Cruza, Edna Zoraida Rojas-Curielb, Berenice Sánchez-Jarac
a Reumatología Pediátrica, Hospital General, Centro Médico Nacional La Raza, IMSS, Mexico City, Mexico
b Cirugía Oncológica Pediátrica, Hospital General, Centro Médico Nacional La Raza, IMSS, Mexico City, Mexico
c Hematología Pediátrica, Hospital General, Centro Médico Nacional La Raza, IMSS, Mexico City, Mexico
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Table 1. Characteristics of Tjalma Syndrome Patients.

Tjalma syndrome or pseudo-pseudo Meigs’ syndrome is a clinical condition characterized by pleural effusion, ascites and elevated CA-125 with no associated benign or malignant ovarian tumor in a patient with systemic lupus erythematosus (SLE). Tjalma described the first case of a patient with SLE, pleural effusion, ascites and elevated CA-125. We report the first case in a 14-year old patient who presented with ascites and pleural effusion refractory to treatment and elevated CA-125, in the absence of an ovarian tumor, that warranted aggressive management.

Tjalma syndrome
Pseudo-pseudo Meigs’
Systemic lupus erythematosus

El síndrome de Tjalma o pseudo-pseudo Meigs es una entidad clínica que se presenta con derrame pleural, ascitis y elevación de CA-125 sin asociación a tumor ovárico benigno o maligno en un paciente con lupus eritematoso sistémico (LES). Tjalma describió el primer caso de un paciente con LES, ascitis, derrame pleural y elevación de CA-125. Presentamos el primer caso en una paciente pediátrica de 14 años, que se presentó con ascitis y derrame pleural refractarios a tratamiento con elevación de CA-125, sin encontrar tumor ovárico, que ameritó manejo agresivo.

Palabras clave:
Síndrome de Tjalma
Pseudo-pseudo Meigs
Lupus eritematoso sistémico


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