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    "textoCompleto" => "<span class="elsevierStyleSections"><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStylePara elsevierViewall">La gota es una de las causas m&#225;s comunes de artritis en los hombres mayores de 40 a&#241;os&#46; La enfermedad se caracteriza por la aparici&#243;n de concentraciones elevadas de &#225;cido &#250;rico en plasma y por la presencia de episodios inflamatorios&#44; habitualmente monoarticulares y recurrentes&#44; que suelen ser intensos y autolimitados&#46;</p><p class="elsevierStylePara elsevierViewall">Los pacientes con gota cr&#243;nica tof&#225;cea &#40;GCT&#41; tienen dep&#243;sitos subcut&#225;neos e intrad&#233;rmicos de cristales de urato monos&#243;dico&#44; llamados tofos<a class="elsevierStyleCrossRefs" href="#bib1"><span class="elsevierStyleSup">1&#8211;3</span></a>&#46; En un estudio previo se report&#243; que hasta el 62&#37; de los pacientes con gota que acuden al servicio de reumatolog&#237;a por primera vez tiene tofos<a class="elsevierStyleCrossRef" href="#bib5"><span class="elsevierStyleSup">5</span></a>&#46; En los pacientes con GCT es frecuente que haya limitaci&#243;n funcional&#44; debida tanto a la enfermedad de base como a las comorbilidades asociadas&#46; La calidad de vida y la capacidad funcional se han estudiado poco en estos pacientes&#46; Con excepci&#243;n del cuestionario GAQ &#40;Gout Assessment Questionnaire &#39;Cuestionario de evaluaci&#243;n de gota&#39;&#41; no hay instrumentos espec&#237;ficos en la valoraci&#243;n de la gota&#44; por tal motivo se han usado instrumentos gen&#233;ricos como el cuestionario HAQ-DI &#40;Health Assessment Questionnaire &#8216;Cuestionario de evaluaci&#243;n de salud&#8217;&#41; y el cuestionario de salud SF &#40;Short Form &#39;Formulario corto&#39;&#41;-36<a class="elsevierStyleCrossRefs" href="#bib4"><span class="elsevierStyleSup">4&#8211;9</span></a>&#46; Se desconoce si otros instrumentos&#44; tales como el AIMS &#40;Arthritis Impact Measurement Scales &#8216;Escala de medici&#243;n del impacto de la artritis&#8217;&#41; o el MOS-20 &#40;Medical Outcomes Study Short Form Health Survey &#8216;Resultados m&#233;dicos del formulario corto del estudio de la encuesta de salud&#8217;&#41;&#44; son &#250;tiles en la medici&#243;n de la calidad de vida relacionada a la salud en los pacientes con GCT&#46;</p><p class="elsevierStylePara elsevierViewall">El objetivo de este estudio fue evaluar la utilidad de los cuestionarios AIMS y MOS-20 en la valoraci&#243;n de la calidad de vida de los pacientes con GCT y la correlaci&#243;n de estos instrumentos con el HAQ-DI&#44; fuerza de prensi&#243;n &#40;FP&#41;&#44; tiempo de marcha &#40;tM&#41; y variables cl&#237;nicas&#46;</p></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStylePara elsevierViewall">Se estudiaron 49 pacientes con GCT&#46; Todos reun&#237;an los criterios de gota del Colegio Americano de Reumatolog&#237;a<a class="elsevierStyleCrossRef" href="#bib17"><span class="elsevierStyleSup">17</span></a>&#46; Se obtuvieron las variables demogr&#225;ficas y cl&#237;nicas &#40;n&#250;mero de articulaciones inflamadas &#91;AI&#93; y de articulaciones dolorosas &#91;AD&#93;&#59; n&#250;mero y localizaci&#243;n de tofos&#59; escalas visuales an&#225;logas &#91;EVA&#93; de valoraci&#243;n del dolor y la percepci&#243;n global de la salud medidas por el pacientes de 0 a 100<span class="elsevierStyleHsp" style=""></span>mm&#44; y se consider&#243; que a mayor puntaje hay mayor dolor y&#44; por tanto&#44; peor estado de salud&#41;&#46; Se document&#243; la presencia de comorbilidades referidas por pacientes&#46; Se consideraron AD a aqu&#233;llas con dolor a la palpaci&#243;n y movilidad&#59; se consideraron AI cuando adem&#225;s del dolor se encontraron datos de flogosis como aumento de volumen&#44; aumento de temperatura local y derrame sinovial&#46; Se consideraron ariculaciones con limitaci&#243;n funcional a aqu&#233;llas con limitaci&#243;n en los arcos de movilidad activos o pasivos&#44; ya sea por dolor&#44; inflamaci&#243;n o secuelas &#40;anquilosis&#44; tofos&#44; etc&#46;&#41;&#46;</p><p class="elsevierStylePara elsevierViewall">La medici&#243;n de la FP se realiz&#243; 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mediante un m&#233;todo propuesto por Bronfman et al para medir caracter&#237;sticas socioecon&#243;micas en Espa&#241;a<a class="elsevierStyleCrossRef" href="#bib20"><span class="elsevierStyleSup">20</span></a>&#44; que toma en cuenta la escolaridad del jefe de familia&#44; las caracter&#237;sticas de la vivienda y el n&#250;mero de personas que habitan en &#233;sta&#46; Tiene un puntaje de 0 a 12 en el que se considera que a menor puntaje es peor el estrato socioecon&#243;mico&#46;</p><p class="elsevierStylePara elsevierViewall">El AIMS es un cuestionario autoaplicado espec&#237;fico para enfermedades reum&#225;ticas&#46; Se compone de 44 entradas agrupadas en 9 categor&#237;as&#46; Las respuestas se eligen de una escala Likert que va de &#171;nunca&#187; a &#171;siempre&#187; y que califica de 0 a 7 de acuerdo con la direcci&#243;n positiva o negativa de la pregunta&#46; Cada categor&#237;a se promedia con el n&#250;mero de preguntas contestadas y se transforma en base 10&#46; Se considera que a mayor calificaci&#243;n es peor la calidad de vida<a class="elsevierStyleCrossRef" href="#bib10"><span class="elsevierStyleSup">10</span></a>&#46;</p><p class="elsevierStylePara elsevierViewall">El MOS-20 es una variante del cuestionario de salud SF-36&#46; Es un cuestionario autoaplicado de 20 preguntas agrupadas en 6 dimensiones &#40;funci&#243;n f&#237;sica&#44; rol funcional&#44; funci&#243;n social&#44; salud mental&#44; percepci&#243;n de la salud y del dolor&#41;&#46; Las respuestas se eligen de una escala Likert&#46; La calificaci&#243;n de cada categor&#237;a se obtiene con el promedio de las preguntas contestadas&#46; Los valores se ajustan sobre la base del sentido de la pregunta para que las calificaciones mayores indiquen una mejor calidad de vida y se transforman linealmente en un intervalo de 0 a 100<a class="elsevierStyleCrossRefs" href="#bib11"><span class="elsevierStyleSup">11&#44;12</span></a>&#46;</p><p class="elsevierStylePara elsevierViewall">El HAQ-DI es un instrumento gen&#233;rico que mide la capacidad funcional del pacientes en la &#250;ltima semana&#46; Es un cuestionario autoaplicado compuesto de 20 preguntas&#44; que se sintetizan en 8 categor&#237;as&#46; Las respuestas se califican en una escala ordinal con valores de 0 a 3&#46; 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No hubo ning&#250;n criterio de selecci&#243;n para los 20 pacientes que tuvieron una segunda valoraci&#243;n y fueron aquellos que acudieron a la siguiente visita&#46;</p></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">An&#225;lisis estad&#237;stico</span><p class="elsevierStylePara elsevierViewall">Para calcular las medidas de tendencia central y de dispersi&#243;n se utilizaron medias y desviaci&#243;n est&#225;ndar en las variables dimensionales&#44; as&#237; como frecuencias en el caso de las variables nominales y ordinales&#46; La homogeneidad se determin&#243; con el alfa de Cronbach&#44; en la que se consideraron significativos los valores superiores a 0&#44;7 y la estabilidad con el coeficiente de correlaci&#243;n intraclase &#40;CCI&#41; en los pacientes con 2 valoraciones &#40;prueba y reprueba&#41; como medidas de reproducibilidad&#46; Se hicieron correlaciones entre los cuestionarios&#44; el tM&#44; la FP y las variables cl&#237;nicas&#46; Para determinar la sensibilidad al cambio se calcul&#243; la diferencia entre ambas mediciones&#44; es decir&#44; el porcentaje de cambio &#40;&#91;X2&#8722;X1&#47;X1&#93;100&#41;&#44; se consideraron significativos los valores mayores al 20&#37; y la correlaci&#243;n entre ambas mediciones por el coeficiente de correlaci&#243;n de Pearson&#46;</p></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStylePara elsevierViewall">Se estudiaron 49 pacientes con GCT&#44; todos de sexo masculino&#44; la edad promedio fue de 53&#177;12 a&#241;os y con una escolaridad promedio de 5&#44;5&#177;3&#44;3 a&#241;os&#46; El estrato socioecon&#243;mico promedio fue de 7&#44;02&#177;2&#44;1&#46; Cuarenta y cuatro pacientes &#40;90&#37;&#41; refirieron tener al menos una comorbilidad&#44; las m&#225;s frecuentes fueron alcoholismo en 35 pacientes &#40;71&#37;&#41;&#44; tabaquismo en 23 pacientes &#40;47&#37;&#41;&#44; hipertensi&#243;n arterial en 11 pacientes &#40;22&#37;&#41;&#44; nefrolitiasis en 9 pacientes &#40;18&#37;&#41;&#44; diabetes mellitus en 2 pacientes &#40;4&#37;&#41; y hepatopat&#237;as en un pacientes &#40;2&#37;&#41;&#46; No hubo diferencias significativas en la calidad de vida o en la capacidad funcional en relaci&#243;n con la presencia o ausencia de las comorbilidades ni en relaci&#243;n con la escolaridad&#44; estrato socioecon&#243;mico o edad en este grupo de pacientes&#46; El tiempo de evoluci&#243;n promedio de la enfermedad fue de 14&#44;9&#177;8&#44;3 a&#241;os&#46; Treinta pacientes ten&#237;an AD &#40;61&#44;2&#37;&#41;&#44; 21 pacientes ten&#237;an articulaciones con limitaci&#243;n funcional &#40;ALF&#41; en los arcos de movilidad &#40;42&#44;9&#37;&#41; y 6 pacientes presentaron AI &#40;12&#44;2&#37;&#41;&#46; La mediana de AD fue de 3 &#40;rango de 0 a 56&#41; y la mediana de AI de 1 &#40;rango de 0 a 3&#41;&#46; Las principales AD y ALF fueron las rodillas&#44; los tobillos&#44; los codos y las mu&#241;ecas&#46; Los tofos se localizaron principalmente en codos&#44; mu&#241;ecas&#44; metacarpofal&#225;ngicas&#44; interfal&#225;ngicas proximales&#44; rodillas&#44; tobillos y primera metatarsofal&#225;ngica&#46; Todos los pacientes presentaron tofos al momento del estudio&#59; 6 &#40;12&#44;2&#37;&#41; eran de localizaci&#243;n intrad&#233;rmica&#46; La mediana del n&#250;mero de tofos fue de 4 &#40;rango de 1 a 32&#41;&#46;</p><p class="elsevierStylePara elsevierViewall">Las EVA de valoraci&#243;n de dolor y salud global en el pacientes fueron de 24&#44;2&#177;25<span class="elsevierStyleHsp" style=""></span>mm y de 50&#44;9&#177;30<span class="elsevierStyleHsp" style=""></span>mm&#44; respectivamente&#46; La FP promedio de ambas manos fue de 159&#177;62 mmHg&#46; La FP estuvo disminuida de forma significativa entre los pacientes con ALF en ambas manos &#40;p&#61;0&#44;000&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl1">tabla 1</a>&#41;&#46; En los pacientes con dolor en las extremidades superiores &#40;n&#61;16&#41; se encontraron diferencias significativas de la FP al ser comparados con los pacientes sin dolor&#46; En la mano derecha la FP fue de 128&#44;06&#177;78&#44;89<span class="elsevierStyleHsp" style=""></span>mmHg para los pacientes con dolor frente a 174&#44;33&#177;56&#44;95<span class="elsevierStyleHsp" style=""></span>mmHg para los pacientes sin dolor &#40;p&#61;0&#44;023&#41;&#59; en la mano izquierda fue de 131&#44;44&#177;65&#44;73<span class="elsevierStyleHsp" style=""></span>mmHg para los pacientes con dolor frente a 171&#44;30&#177;56<span class="elsevierStyleHsp" style=""></span>mmHg para los pacientes sin dolor &#40;p&#61;0&#44;032&#41;&#46; La FP se correlacion&#243; con la presencia de ALF &#40;r&#61;&#8722;0&#44;6&#59; p&#61;0&#44;000&#41; y con la EVA de dolor &#40;r&#61;&#8722;0&#44;328&#59; p&#61;0&#44;022&#41;&#46; La correlaci&#243;n de la FP entre ambas manos fue de 0&#44;83 &#40;p&#61;0&#44;000&#41;&#46;</p><elsevierMultimedia ident="tbl1"></elsevierMultimedia><p class="elsevierStylePara elsevierViewall">El tM promedio de 15 m fue de 0&#44;14&#177;0&#44;05 min&#46; El tM fue mayor en los pacientes con AD &#40;0&#44;16&#177;0&#44;65<span class="elsevierStyleHsp" style=""></span>min&#41; que en los pacientes sin dolor articular &#40;0&#44;12&#177;0&#44;02<span class="elsevierStyleHsp" style=""></span>min&#41; &#40;p&#61;0&#44;022&#41;&#46; Tambi&#233;n se encontr&#243; una diferencia significativa del tM entre los pacientes con ALF y sin ALF &#40;0&#44;17&#177;0&#44;07<span class="elsevierStyleHsp" style=""></span>min frente a 0&#44;13&#177;0&#44;03<span class="elsevierStyleHsp" style=""></span>min&#44; respectivamente&#59; p&#61;0&#44;004&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46; Los pacientes con dolor en las extremidades inferiores &#40;n&#61;21&#41; tuvieron mayor tM que los pacientes sin dolor&#58; 0&#44;17&#177;0&#44;07<span class="elsevierStyleHsp" style=""></span>min frente a 0&#44;12&#177;0&#44;02<span class="elsevierStyleHsp" style=""></span>min &#40;p&#61;0&#44;001&#41;&#46; El tM s&#243;lo se correlacion&#243; con la presencia de AD &#40;r&#61;0&#44;3&#59; p&#61;0&#44;042&#41;&#46; No hubo diferencias significativas entre los pacientes con inflamaci&#243;n articular y sin inflamaci&#243;n articular&#46;</p><elsevierMultimedia ident="tbl2"></elsevierMultimedia><p class="elsevierStylePara elsevierViewall">A continuaci&#243;n se presentan los resultados por cada instrumento en relaci&#243;n con la capacidad funcional y la calidad de vida&#46;</p><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Escala de medici&#243;n del impacto de la artritis</span><p class="elsevierStylePara elsevierViewall">Las categor&#237;as m&#225;s afectadas fueron el dolor&#44; la actividad social&#44; la actividad f&#237;sica y la movilidad &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46; En los pacientes con AD la movilidad&#44; el desempe&#241;o social&#44; las actividades cotidianas y el dolor tuvieron calificaciones significativamente mayores que en aqu&#233;llos sin dolor&#46; En los pacientes con ALF&#44; las categor&#237;as de actividad f&#237;sica&#44; destreza&#44; desempe&#241;o social y dolor tuvieron calificaciones significativamente mayores &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46;</p></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Resultados m&#233;dicos del formulario corto del estudio de la encuesta de salud</span><p class="elsevierStylePara elsevierViewall">Las categor&#237;as m&#225;s afectadas fueron el dolor y la percepci&#243;n de la salud &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46; En los pacientes con AD&#44; las categor&#237;as de dolor y funci&#243;n social tuvieron calificaciones significativamente menores en comparaci&#243;n con los pacientes sin dolor&#46; En los pacientes con ALF&#44; el rol funcional&#44; la funci&#243;n social y el dolor tuvieron calificaciones significativamente menores &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46;</p></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Cuestionario de evaluaci&#243;n de salud</span><p class="elsevierStylePara elsevierViewall">Este instrumento se emple&#243; para validar la convergencia de los otros 2 cuestionarios&#46; Las calificaciones promedio del HAQ-DI estuvieron por debajo de uno en todas las categor&#237;as&#44; las m&#225;s afectadas fueron el levantarse&#44; la higiene&#44; las actividades&#44; y el sujetar y alcanzar cosas&#46; La media de la calificaci&#243;n del HAQ-DI fue de 0&#44;43&#177;0&#44;56 &#40;intervalo de confianza &#91;IC&#93; del 95&#37;&#44; rango de 0&#44;27 a 0&#44;60&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46; En los pacientes que ten&#237;an ALF&#44; el HAQ-DI fue de 0&#44;74&#177;0&#44;61&#46; En los pacientes sin ALF&#44; el HAQ-DI fue de 0&#44;18&#177;0&#44;37 &#40;p&#61;0&#44;000&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46;</p></span></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Correlaciones de los cuestionarios</span><p class="elsevierStylePara elsevierViewall">El HAQ-DI se correlacion&#243; con la FP de ambas manos &#40;r&#61;&#8722;0&#44;6&#59; p&#61;0&#44;000 en ambas&#41;&#44; la ALF &#40;r&#61;0&#44;6&#59; p&#61;0&#44;000&#41; y la EVA de dolor &#40;r&#61;0&#44;6&#59; p&#61;0&#44;000&#41;&#46; Asimismo&#44; se correlacion&#243; con las categor&#237;as del AIMS de movilidad &#40;r&#61;0&#44;6&#59; p&#61;0&#44;000&#41;&#44; actividad f&#237;sica &#40;r&#61;0&#44;4&#59; p&#61;0&#44;006&#41;&#44; destreza &#40;r&#61;0&#44;4&#59; p&#61;0&#44;011&#41;&#44; desempe&#241;o social &#40;r&#61;0&#44;5&#59; p&#61;0&#44;000&#41;&#44; actividad social &#40;r&#61;0&#44;4&#59; p&#61;0&#44;010&#41;&#44; actividades cotidianas &#40;r&#61;0&#44;4&#59; p&#61;0&#44;006&#41; y dolor &#40;r&#61;0&#44;4&#59; p&#61;0&#44;020&#41;&#44; pero no con depresi&#243;n &#40;r&#61;0&#44;3&#59; p&#61;0&#44;072&#41; o ansiedad &#40;r&#61;0&#44;1&#59; p&#61;0&#44;45&#41;&#46; Se correlacion&#243; con el MOS-20 en las dimensiones de funci&#243;n f&#237;sica &#40;r&#61;&#8722;0&#44;5&#59; p&#61;0&#44;000&#41;&#44; rol funcional &#40;r&#61;&#8722;0&#44;5&#59; p&#61;0&#44;001&#41;&#44; funci&#243;n social &#40;r&#61;&#8722;0&#44;5&#59; p&#61;0&#44;001&#41;&#44; percepci&#243;n de la salud &#40;r&#61;&#8722;0&#44;3&#59; p&#61;0&#44;021&#41; y dolor &#40;r&#61;&#8722;0&#44;3&#59; p&#61;0&#44;035&#41;&#44; pero no se correlacion&#243; con la salud mental &#40;r&#61;&#8722;0&#44;1&#59; p&#61;0&#44;38&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl4">tabla 4</a>&#41;&#46;</p></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Sensibilidad al cambio</span><p class="elsevierStylePara elsevierViewall">Se obtuvo una segunda medici&#243;n de los instrumentos en s&#243;lo 20 pacientes que acudieron a una segunda valoraci&#243;n despu&#233;s de 8 semanas de la visita basal&#46; No hubo diferencias significativas en las variables demogr&#225;ficas o cl&#237;nicas entre los pacientes que acudieron a la segunda visita en comparaci&#243;n con aquellos pacientes que no acudieron&#46; Tampoco hubo diferencias en la medici&#243;n basal ni en la medici&#243;n final en el grupo total&#44; debido a que la mayor&#237;a de los pacientes se encontraba en per&#237;odo intercr&#237;tico&#46; Al comparar la primera con la segunda medici&#243;n se encontraron porcentajes de cambio mayores al 20&#37; en las categor&#237;as de destreza&#44; desempe&#241;o social&#44; actividades cotidianas&#44; dolor y depresi&#243;n del AIMS y en las dimensiones de funci&#243;n f&#237;sica&#44; funci&#243;n social&#44; percepci&#243;n de la salud &#40;salud global&#41; y dolor del MOS-20&#46; En la prueba y en la reprueba se observaron mejores puntajes del CCI en los componentes de movilidad&#44; actividad f&#237;sica y destreza del AIMS y en los de funci&#243;n f&#237;sica&#44; rol funcional y dolor del MOS-20&#46; S&#243;lo se encontraron correlaciones significativas entre la primera y la segunda valoraci&#243;n en los componentes de movilidad y destreza del AIMS&#44; la salud mental del MOS-20 y en el HAQ-DI &#40;<a class="elsevierStyleCrossRefs" href="#tbl3">tablas 3 y 4</a>&#41;&#46;</p><elsevierMultimedia ident="tbl3"></elsevierMultimedia><elsevierMultimedia ident="tbl4"></elsevierMultimedia></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Discusi&#243;n</span><p class="elsevierStylePara elsevierViewall">En el presente estudio se aplicaron los cuestionarios AIMS y MOS-20 a pacientes con gota&#59; los cuestionarios demostraron tener una buena reproducibilidad as&#237; como moderada sensibilidad al cambio para la medici&#243;n de la capacidad funcional y de la calidad de vida&#46;</p><p class="elsevierStylePara elsevierViewall">El AIMS tuvo una reproducibilidad &#40;&#945; de Cronbach de 0&#44;66 a 0&#44;96 entre los diferentes componentes&#41;&#44; similar a la reportada para pacientes con artritis reumatoide &#40;AR&#41; &#40;de 0&#44;71 a 0&#44;93&#41;&#46; Las categor&#237;as m&#225;s afectadas fueron el dolor &#40;5&#44;94&#177;1&#44;88&#41;&#44; la actividad social &#40;5&#44;76&#177;1&#44;92&#41; &#40;es posible que la presencia de tofos sea la causa de este fen&#243;meno&#41;&#44; la actividad f&#237;sica &#40;4&#44;44&#177;1&#44;93&#41; y la movilidad &#40;4&#44;30&#177;1&#44;81&#41;&#46; Por otra parte&#44; las categor&#237;as menos afectadas fueron las actividades cotidianas &#40;2&#44;66&#177;2&#44;20&#41;&#44; el desempe&#241;o social &#40;2&#44;67&#177;1&#44;60&#41; y la destreza &#40;2&#44;68&#177;1&#44;68&#41;&#46; La mayor&#237;a de las calificaciones fueron similares a las reportadas en los pacientes con AR<a class="elsevierStyleCrossRef" href="#bib10"><span class="elsevierStyleSup">10</span></a>&#44; con excepci&#243;n de la destreza&#44; la depresi&#243;n y la ansiedad que est&#225;n m&#225;s afectadas en los pacientes con AR&#44; mientras que la actividad social se ve m&#225;s afectada en los pacientes con gota&#46;</p><p class="elsevierStylePara elsevierViewall">Se encontr&#243; una correlaci&#243;n divergente&#44; de moderada a buena&#44; entre las categor&#237;as de movilidad&#44; actividad f&#237;sica y destreza del AIMS&#44; con la funci&#243;n f&#237;sica y el rol funcional del MOS-20&#46; La salud mental y la funci&#243;n social del MOS-20 se correlacionaron con situaciones de depresi&#243;n y ansiedad reflejadas en el AIMS&#46; Las categor&#237;as de dolor de ambos instrumentos tuvieron una correlaci&#243;n significativa&#46; Las calificaciones de movilidad&#44; actividad f&#237;sica&#44; destreza&#44; desempe&#241;o social y dolor fueron significativamente mayores en los pacientes con ALF&#46; Todas las mediciones del MOS-20 se encontraron disminuidas en este grupo de pacientes&#44; las m&#225;s afectadas fueron la percepci&#243;n de la salud &#40;34&#44;26&#177;16&#44;55&#41; y el dolor &#40;37&#44;23&#177;34&#44;53&#41;&#44; y la menos afectada fue la salud mental &#40;70&#44;33&#177;21&#44;59&#41;&#46; La misma tendencia se observa al hacer la medici&#243;n de la calidad de vida con SF-36&#44; en el que hay mayor afecci&#243;n del componente f&#237;sico que del componente mental<a class="elsevierStyleCrossRef" href="#bib9"><span class="elsevierStyleSup">9</span></a>&#46; El rol funcional&#44; la funci&#243;n f&#237;sica y el dolor se encontraron significativamente menores en los pacientes con ALF&#46; La presencia de afecci&#243;n en las extremidades superiores disminuy&#243; la FP&#44; mientras que la afecci&#243;n en las extremidades inferiores prolong&#243; el tM&#46;</p><p class="elsevierStylePara elsevierViewall">El HAQ-DI tuvo una correlaci&#243;n significativa con la EVA de dolor&#44; el tM&#44; la FP&#44; la presencia de ALF y con los dominios relacionados con la funci&#243;n f&#237;sica m&#225;s que con los de salud mental del AIMS y del MOS-20&#46; Esto concuerda con lo reportado previamente&#44; es decir&#44; hay una mejor correlaci&#243;n del HAQ-DI con los componentes de funci&#243;n f&#237;sica as&#237; como una correlaci&#243;n baja con los componentes de salud mental del cuestionario de salud SF-36<a class="elsevierStyleCrossRef" href="#bib8"><span class="elsevierStyleSup">8</span></a>&#46; Debido a que en este estudio s&#243;lo se incluyeron pacientes con GCT y a que la mayor&#237;a se encontraba en per&#237;odo intercr&#237;tico&#44; no se encontraron diferencias significativas con relaci&#243;n a la presencia de tofos y AI como en otros trabajos que han incluido pacientes con un espectro m&#225;s amplio de la enfermedad<a class="elsevierStyleCrossRefs" href="#bib5"><span class="elsevierStyleSup">5&#8211;8</span></a>&#46; En un estudio de 375 pacientes con gota&#44; de los cuales el 62&#37; ten&#237;a tofos&#44; se encontr&#243; que en los pacientes con 5 o m&#225;s tofos la calificaci&#243;n del HAQ-DI era significativamente mayor cuando se la comparaba con los que ten&#237;an menos de 5 tofos &#40;0&#44;38&#177;0&#44;84 frente a 0&#44;04&#177;0&#44;15&#59; p&#61;0&#44;000&#41;<a class="elsevierStyleCrossRef" href="#bib5"><span class="elsevierStyleSup">5</span></a>&#46; &#193;lvarez-Hern&#225;ndez et al encontraron una tendencia similar en un estudio multic&#233;ntrico que incluy&#243; 206 pacientes&#44; de los cuales el 37&#37; ten&#237;a tofos&#46; En los pacientes con tofos el HAQ-DI fue de 1&#44;01&#177;0&#44;84&#44; mientras que en los pacientes sin tofos fue de 0&#44;35&#177;0&#44;56 &#40;p&#61;0&#44;000&#41;<a class="elsevierStyleCrossRef" href="#bib8"><span class="elsevierStyleSup">8</span></a>&#46; &#193;lvarez-Nemegyei tambi&#233;n reporta la presencia de tofos como un factor de riesgo para la presencia de discapacidad musculoesquel&#233;tica &#40;DME&#41; con un riesgo relativo de 4&#44;3 &#40;IC del 95&#37;&#44; rango de 1&#44;2 a 15&#44;1&#41;&#46; Asimismo&#44; tambi&#233;n reporta una diferencia significativa de la calificaci&#243;n del HAQ-DI entre los pacientes con DME comparados con aquellos pacientes sin DME &#40;0&#44;17&#177;0&#44;21 frente a 0&#44;02&#177;0&#44;0004&#59; p&#61;0&#44;000&#41;<a class="elsevierStyleCrossRef" href="#bib7"><span class="elsevierStyleSup">7</span></a>&#46; &#201;sta es una situaci&#243;n similar a la que se encuentra en este trabajo entre los pacientes con ALF y sin ALF &#40;0&#44;74&#177;0&#44;61 frente a 0&#44;18&#177;0&#44;37&#59; p&#61;0&#44;000&#41;&#46;</p><p class="elsevierStylePara elsevierViewall">La sensibilidad al cambio fue mejor en los componentes de funci&#243;n f&#237;sica del AIMS y del MOS-20&#44; pero fue pobre en los componentes de salud mental&#46;</p><p class="elsevierStylePara elsevierViewall">Una de las principales limitaciones del estudio es que s&#243;lo se incluyeron los pacientes con GCT en per&#237;odo intercr&#237;tico&#46; Debido a esta restricci&#243;n no fue posible realizar comparaciones con pacientes que tuvieran ataque agudo o con pacientes sin la presencia de tofos&#44; lo que posibilitar&#237;a tener un espectro m&#225;s amplio y verificar si estos instrumentos tienen diferencias significativas entre los subgrupos de pacientes&#46;</p><p class="elsevierStylePara elsevierViewall">Este estudio concluye que el AIMS y el MOS-20 pueden ser &#250;tiles en la valoraci&#243;n de la capacidad funcional y de la calidad de vida de los pacientes con gota&#44; tanto en la pr&#225;ctica cl&#237;nica como en estudios de investigaci&#243;n&#46;</p></span></span>"
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              "titulo" => "Escala de medici&#243;n del impacto de la artritis"
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            1 => array:1 [
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      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">Hay pocos instrumentos en el estudio de gota validados para evaluar la actividad&#44; la capacidad funcional o la calidad de vida de los pacientes&#46; Se desconoce si los instrumentos gen&#233;ricos como el cuestionario MOS-20 &#40;Medical Outcomes Study Short Form Health Survey &#8216;Resultados m&#233;dicos del formulario corto del estudio de la encuesta de salud&#8217;&#41; o los instrumentos espec&#237;ficos para otras enfermedades&#44; como el cuestionario AIMS &#40;Arthritis Impact Measurement Scales &#8216;Escala de medici&#243;n del impacto de la artritis&#8217;&#41; puedan aplicarse a pacientes con gota&#46;</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Evaluar las caracter&#237;sticas clinim&#233;tricas de los cuestionarios MOS-20 y AIMS y su correlaci&#243;n con el cuestionario HAQ-DI &#40;Health Assessment Questionnaire &#8216;Cuestionario de evaluaci&#243;n de salud&#8217;&#41; as&#237; como con variables cl&#237;nicas en los pacientes con gota cr&#243;nica tof&#225;cea &#40;GCT&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se incluyeron 49 pacientes con GCT&#46; Se obtuvieron las variables demogr&#225;ficas y cl&#237;nicas&#46; Se aplicaron los 3 cuestionarios en la valoraci&#243;n basal&#46; En 20 pacientes se realiz&#243; una segunda evaluaci&#243;n despu&#233;s de 8 semanas&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Todos los pacientes fueron de sexo masculino&#46; El tiempo de evoluci&#243;n de la enfermedad fue de 14&#44;9&#177;8&#44;3 a&#241;os&#46; El HAQ-DI fue de 0&#44;43&#177;0&#44;56 con un alfa de Cronbach &#40;&#945;C&#41; de 0&#44;95 y un coeficiente de correlaci&#243;n intraclase &#40;CCI&#41; de 0&#44;86&#46; El MOS-20 tuvo un &#945;C de 0&#44;68 a 1&#44;0 y un CCI de 0&#44;27 a 0&#44;61 entre las diferentes dimensiones&#46; El AIMS tuvo un &#945;C de 0&#44;66 a 0&#44;96 y un CCI de 0&#44;11 a 0&#44;79 entre los diferentes componentes&#46; La reproducibilidad fue mejor en los componentes f&#237;sicos que en los componentes de salud mental tanto del MOS-20 como del AIMS&#46; Los cuestionarios MOS-20&#44; AIMS y HAQ-DI correlacionaron con la presencia de articulaciones con limitaci&#243;n funcional&#46; No se encontraron diferencias significativas entre los pacientes con articulaciones inflamadas ni con tofos&#46; El HAQ-DI se correlacion&#243; mejor con las variables del componente f&#237;sico que con las del componente mental de los cuestionarios AIMS y MOS-20&#46;</p> <span class="elsevierStyleSectionTitle">Conclusi&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">Los cuestionarios AIMS&#44; MOS-20 y HAQ-DI son &#250;tiles para valorar la capacidad funcional y la calidad de vida en los pacientes con GCT&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">In gout there are few instruments validated for the evaluation of activity&#44; functional capacity or quality of life&#46; It is not known if generic instruments such as the MOS-20&#44; or specific for other illnesses&#44; such as the AIMS&#44; can be applied to patients with Gout&#46;</p> <span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To evaluate the clinimetric characteristic of the MOS-20 and AIMS questionnaires&#44; and their correlation with HAQ-DI&#44; as well as with clinical variables in patient with tophaceous gout &#40;TG&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p class="elsevierStyleSimplePara elsevierViewall">49 patients with TG were included&#46; Demographic and clinical variables were obtained&#46; The 3 questionnaires were applied at the basal evaluation&#46; A second evaluation was applied to 20 patients&#44; 8 weeks later&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">All patients were male&#46; The time of since onset of the illness was 14&#46;9&#177;8&#46;3 years&#46; The HAQ-DI was 0&#46;43&#177;0&#46;56 with an alpha of Cronbach &#40;&#945;C&#41; of 0&#46;95 and the intraclass correlation coefficient &#40;ICC&#41; was 0&#46;86&#46; The MOS-20 had an &#945;C of 0&#46;68 to 1&#46;0 and a ICC of 0&#46;27 to 0&#46;61 between the several components&#46; The AIMS had an &#945;C of 0&#46;66 to 0&#46;96&#44; and a ICC of 0&#46;11 to 0&#46;79 between the several components&#46; Reliability was better between the physical components in MOS-20 and AIMS&#46; The MOS-20&#44; AIMS and the HAQ-DI correlated with the presence of joints with functional limitation&#46; There weren&#8217;t any significant differences among the patients with inflamed joints&#44; nor in those with tophi&#46; The HAQ-DI was best correlated with the physical component than with the mental component of the AIMS and the MOS-20&#46;</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p class="elsevierStyleSimplePara elsevierViewall">The AIMS&#44; the MOS-20 and the HAQ-DI are useful in measuring the functional capacity and the quality of life in patient with TG&#46;</p>"
      ]
    ]
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          "leyenda" => "<p class="elsevierStyleSimplePara elsevierViewall">AIMS&#58; escala de medici&#243;n del impacto de la artritis&#59; ALF&#58; articulaci&#243;n con limitaci&#243;n funcional&#59; DE&#58; desviaci&#243;n est&#225;ndar&#59; FP&#58; fuerza de prensi&#243;n&#59; HAQ-DI&#58; cuestionario de evaluaci&#243;n de salud&#59; MOS-20&#58; resultados m&#233;dicos del formulario corto del estudio de la encuesta de salud&#59; tM&#58; tiempo de marcha&#46;</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Con ALF &#40;n &#61; 21&#41;&#44; media &#40;DE&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Sin ALF &#40;n &#61; 28&#41;&#44; media &#40;DE&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">P&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">tM &#40;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;17 &#40;0&#44;07&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;13 &#40;0&#44;033&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;004&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">FP mano derecha &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">112&#44;52 &#40;58&#44;07&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">194&#44;25 &#40;51&#44;86&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">FP mano izquierda &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">123&#44;81 &#40;53&#44;96&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">184&#44;14 &#40;54&#44;55&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HAQ-DI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;74 &#40;0&#44;61&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;18 &#40;0&#44;37&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">AIMS</span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Movilidad&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;14 &#40;2&#44;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;70 &#40;1&#44;12&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividad f&#237;sica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;41 &#40;1&#44;64&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;74 &#40;1&#44;84&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;002&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Destreza&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;51 &#40;1&#44;96&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;08 &#40;1&#44;16&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;003&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Desempe&#241;o social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;64 &#40;1&#44;85&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;99 &#40;0&#44;93&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividad social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;38 &#40;1&#44;66&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;35 &#40;2&#44;01&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;072&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividades cotidianas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;05 &#40;2&#44;35&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;40 &#40;2&#44;10&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;33&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Dolor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;62 &#40;1&#44;66&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;46 &#40;1&#44;91&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;039&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Depresi&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;88 &#40;2&#44;19&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;85 &#40;2&#44;11&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;96&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Ansiedad&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">4&#44;36 &#40;1&#44;55&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;19 &#40;1&#44;68&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;73&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">MOS-20</span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Funci&#243;n f&#237;sica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">56&#44;08 &#40;39&#44;80&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">76&#44;79 &#40;32&#44;10&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;052&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Rol funcional&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">37&#44;50 &#40;40&#44;96&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">65&#44;18 &#40;39&#44;87&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;023&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Funci&#243;n social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">48&#44;00 &#40;40&#44;73&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">81&#44;43 &#40;23&#44;05&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Salud mental&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">66&#44;00 &#40;24&#44;02&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">73&#44;43 &#40;19&#44;54&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Percepci&#243;n de la salud&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">29&#44;65 &#40;17&#44;05&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">37&#44;59 &#40;15&#44;65&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Dolor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">23&#44;75 &#40;28&#44;65&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">47&#44;22 &#40;35&#44;58&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;019&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "leyenda" => "<p class="elsevierStyleSimplePara elsevierViewall">AIMS&#58; escala de medici&#243;n del impacto de la artritis&#59; DE&#58; desviaci&#243;n est&#225;ndar&#59; HAQ-DI&#58; cuestionario de evaluaci&#243;n de salud&#59; MOS-20&#58; resultados m&#233;dicos del formulario corto del estudio de la encuesta de salud&#46;</p>"
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                  \t\t\t\t\tvoid\n
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                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Instrumento&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">Media &#40;DE&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">Rango&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">Alfa de Cronbach&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">4&#44;30 &#40;1&#44;81&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">1&#44;43&#8211;9&#44;29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">0&#44;67&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividad f&#237;sica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;44 &#40;1&#44;93&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;8&#44;29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">0&#44;66&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Destreza&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;68 &#40;1&#44;68&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;8&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;83&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Desempe&#241;o social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;67 &#40;1&#44;60&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;7&#44;34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;76&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividad social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;76 &#40;1&#44;92&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;75&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividades cotidianas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;66 &#40;2&#44;20&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;96&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Dolor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;94 &#40;1&#44;88&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;14&#8211;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;77&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Depresi&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;86 &#40;2&#44;12&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;9&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">Ansiedad&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " colspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">MOS-20</span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Funci&#243;n f&#237;sica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">68&#44;16 &#40;36&#44;59&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Rol funcional&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Funci&#243;n social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">67&#44;50 &#40;35&#44;40&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">0&#8211;100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">1&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Salud mental&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">70&#44;33 &#40;21&#44;59&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">24&#8211;100&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">0&#44;68&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Percepci&#243;n de la salud&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">34&#44;26 &#40;16&#44;55&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Dolor&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">HAQ-DI&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">0&#44;43 &#40;0&#44;56&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">0&#44;95&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "leyenda" => "<p class="elsevierStyleSimplePara elsevierViewall">AIMS&#58; escala de medici&#243;n del impacto de la artritis&#59; CCI&#58; coeficiente de correlaci&#243;n intraclase&#59; DE&#58; desviaci&#243;n est&#225;ndar&#59; HAQ-DI&#58; cuestionario de evaluaci&#243;n de salud&#59; IC&#58; intervalo de confianza&#59; MOS-20&#58; resultados m&#233;dicos del formulario corto del estudio de la encuesta de la salud&#59; NS&#58; no significativo&#46;</p>"
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                  \t\t\t\t" style="border-bottom: 2px solid black">Instrumento&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Visita basal&#44; media &#40;DE&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HAQ-DI&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">0&#44;86 &#40;0&#44;65&#8211;0&#44;95&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">AIMS</span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Movilidad&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">4&#44;6 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">0&#44;63 &#40;0&#44;004&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">0&#44;70 &#40;0&#44;25&#8211;0&#44;88&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividad f&#237;sica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">4&#44;7 &#40;1&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">4&#44;0 &#40;3&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;30 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;66 &#40;0&#44;34&#8211;0&#44;72&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Destreza&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;0 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;2 &#40;2&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;45 &#40;0&#44;045&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;60 &#40;&#8722;0&#44;02&#8211;0&#44;84&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Desempe&#241;o social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;2 &#40;1&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;8 &#40;3&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">64&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;068 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;11 &#40;&#8722;1&#44;25&#8211;0&#44;65&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividad social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;7 &#40;2&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;9 &#40;3&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;34 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;48 &#40;&#8722;0&#44;36&#8211;0&#44;80&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividades cotidianas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;9 &#40;2&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;0 &#40;2&#44;0&#41;<a class="elsevierStyleCrossRef" href="#tblfn3a"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">209&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;27 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;41 &#40;&#8722;0&#44;54&#8211;0&#44;77&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Dolor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;3 &#40;2&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;9 &#40;2&#44;3&#41;<a class="elsevierStyleCrossRef" href="#tblfn3a"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;51&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;20 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;33 &#40;&#8722;0&#44;73&#8211;0&#44;74&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Depresi&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;0 &#40;2&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;5 &#40;2&#44;3&#41;<a class="elsevierStyleCrossRef" href="#tblfn3b"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">67&#44;27&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;23 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;38 &#40;&#8722;0&#44;62&#8211;0&#44;76&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Ansiedad&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;4 &#40;1&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;5 &#40;2&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;4&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;13 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;25 &#40;&#8722;0&#44;33&#8211;0&#44;53&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">MOS-20</span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Funci&#243;n f&#237;sica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">61&#44;2 &#40;36&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">74&#44;8 &#40;32&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">31&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;33 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;49 &#40;&#8722;0&#44;28&#8211;0&#44;80&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Rol funcional&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">51&#44;3 &#40;40&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">65&#44;0 &#40;40&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;44 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;61 &#40;0&#44;01&#8211;0&#44;85&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Funci&#243;n social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">58&#44;0 &#40;37&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">75&#44;0 &#40;38&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">31&#44;12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;22 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;37 &#40;&#8722;0&#44;61&#8211;0&#44;75&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Salud mental&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">74&#44;4 &#40;19&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">65&#44;0 &#40;40&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;2&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;30 &#40;0&#44;04&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;27 &#40;&#8722;0&#44;85&#8211;0&#44;71&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Percepci&#243;n de la salud&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">32&#44;0 &#40;16&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">57&#44;0 &#40;32&#44;6&#41;<a class="elsevierStyleCrossRef" href="#tblfn3a"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">149&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;23 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;30 &#40;&#8722;0&#44;78&#8211;0&#44;72&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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Medición de la calidad de vida asociada a la salud y a la capacidad funcional en pacientes con gota crónica tofácea
Measurement of health-related quality of life and functional capacity in patients with chronic tophaceous gout
Everardo Álvarez-Hernández
Autor para correspondencia
everalvh@yahoo.com.mx

Autor para correspondencia.
, Jorge A. Zamudio-Lerma, Gabriela Burgos-Martínez, Sandra E. Álvarez-Etchegaray, Ingris Pelaez-Ballestas, J. Vázquez-Mellado
Servicio de Reumatología, Hospital General de México, México D.F., México
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    "textoCompleto" => "<span class="elsevierStyleSections"><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStylePara elsevierViewall">La gota es una de las causas m&#225;s comunes de artritis en los hombres mayores de 40 a&#241;os&#46; La enfermedad se caracteriza por la aparici&#243;n de concentraciones elevadas de &#225;cido &#250;rico en plasma y por la presencia de episodios inflamatorios&#44; habitualmente monoarticulares y recurrentes&#44; que suelen ser intensos y autolimitados&#46;</p><p class="elsevierStylePara elsevierViewall">Los pacientes con gota cr&#243;nica tof&#225;cea &#40;GCT&#41; tienen dep&#243;sitos subcut&#225;neos e intrad&#233;rmicos de cristales de urato monos&#243;dico&#44; llamados tofos<a class="elsevierStyleCrossRefs" href="#bib1"><span class="elsevierStyleSup">1&#8211;3</span></a>&#46; En un estudio previo se report&#243; que hasta el 62&#37; de los pacientes con gota que acuden al servicio de reumatolog&#237;a por primera vez tiene tofos<a class="elsevierStyleCrossRef" href="#bib5"><span class="elsevierStyleSup">5</span></a>&#46; En los pacientes con GCT es frecuente que haya limitaci&#243;n funcional&#44; debida tanto a la enfermedad de base como a las comorbilidades asociadas&#46; La calidad de vida y la capacidad funcional se han estudiado poco en estos pacientes&#46; Con excepci&#243;n del cuestionario GAQ &#40;Gout Assessment Questionnaire &#39;Cuestionario de evaluaci&#243;n de gota&#39;&#41; no hay instrumentos espec&#237;ficos en la valoraci&#243;n de la gota&#44; por tal motivo se han usado instrumentos gen&#233;ricos como el cuestionario HAQ-DI &#40;Health Assessment Questionnaire &#8216;Cuestionario de evaluaci&#243;n de salud&#8217;&#41; y el cuestionario de salud SF &#40;Short Form &#39;Formulario corto&#39;&#41;-36<a class="elsevierStyleCrossRefs" href="#bib4"><span class="elsevierStyleSup">4&#8211;9</span></a>&#46; Se desconoce si otros instrumentos&#44; tales como el AIMS &#40;Arthritis Impact Measurement Scales &#8216;Escala de medici&#243;n del impacto de la artritis&#8217;&#41; o el MOS-20 &#40;Medical Outcomes Study Short Form Health Survey &#8216;Resultados m&#233;dicos del formulario corto del estudio de la encuesta de salud&#8217;&#41;&#44; son &#250;tiles en la medici&#243;n de la calidad de vida relacionada a la salud en los pacientes con GCT&#46;</p><p class="elsevierStylePara elsevierViewall">El objetivo de este estudio fue evaluar la utilidad de los cuestionarios AIMS y MOS-20 en la valoraci&#243;n de la calidad de vida de los pacientes con GCT y la correlaci&#243;n de estos instrumentos con el HAQ-DI&#44; fuerza de prensi&#243;n &#40;FP&#41;&#44; tiempo de marcha &#40;tM&#41; y variables cl&#237;nicas&#46;</p></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStylePara elsevierViewall">Se estudiaron 49 pacientes con GCT&#46; Todos reun&#237;an los criterios de gota del Colegio Americano de Reumatolog&#237;a<a class="elsevierStyleCrossRef" href="#bib17"><span class="elsevierStyleSup">17</span></a>&#46; Se obtuvieron las variables demogr&#225;ficas y cl&#237;nicas &#40;n&#250;mero de articulaciones inflamadas &#91;AI&#93; y de articulaciones dolorosas &#91;AD&#93;&#59; n&#250;mero y localizaci&#243;n de tofos&#59; escalas visuales an&#225;logas &#91;EVA&#93; de valoraci&#243;n del dolor y la percepci&#243;n global de la salud medidas por el pacientes de 0 a 100<span class="elsevierStyleHsp" style=""></span>mm&#44; y se consider&#243; que a mayor puntaje hay mayor dolor y&#44; por tanto&#44; peor estado de salud&#41;&#46; Se document&#243; la presencia de comorbilidades referidas por pacientes&#46; Se consideraron AD a aqu&#233;llas con dolor a la palpaci&#243;n y movilidad&#59; se consideraron AI cuando adem&#225;s del dolor se encontraron datos de flogosis como aumento de volumen&#44; aumento de temperatura local y derrame sinovial&#46; Se consideraron ariculaciones con limitaci&#243;n funcional a aqu&#233;llas con limitaci&#243;n en los arcos de movilidad activos o pasivos&#44; ya sea por dolor&#44; inflamaci&#243;n o secuelas &#40;anquilosis&#44; tofos&#44; etc&#46;&#41;&#46;</p><p class="elsevierStylePara elsevierViewall">La medici&#243;n de la FP se realiz&#243; pidiendo al pacientes que apretara el brazalete de un esfigmoman&#243;metro previamente inflado a 20<span class="elsevierStyleHsp" style=""></span>mmHg&#59; se registr&#243; el punto m&#225;ximo obtenido despu&#233;s de 3 intentos por cada mano&#46; Al final se calcul&#243; el promedio de FP en ambas manos&#46; Se utiliz&#243; para valorar la afecci&#243;n de las extremidades superiores&#46;</p><p class="elsevierStylePara elsevierViewall">El tM se expres&#243; en minutos &#40;medida funcional semicuantitativa&#44; aceptada para la evaluaci&#243;n del funcionamiento de las extremidades inferiores&#41;&#46; Se cronometr&#243; el tiempo que tarda un pacientes en caminar 15<span class="elsevierStyleHsp" style=""></span>m planos y libres de obst&#225;culos y se emple&#243;&#44; en caso necesario&#44; los implementos que requiriera para caminar &#40;por ejemplo&#58; bast&#243;n&#44; muletas&#44; andadera&#44; etc&#46;&#41; y se utiliz&#243; para valorar la afecci&#243;n en las extremidades inferiores<a class="elsevierStyleCrossRefs" href="#bib18"><span class="elsevierStyleSup">18&#44;19</span></a>&#46;</p><p class="elsevierStylePara elsevierViewall">El estrato socioecon&#243;mico se calcul&#243; mediante un m&#233;todo propuesto por Bronfman et al para medir caracter&#237;sticas socioecon&#243;micas en Espa&#241;a<a class="elsevierStyleCrossRef" href="#bib20"><span class="elsevierStyleSup">20</span></a>&#44; que toma en cuenta la escolaridad del jefe de familia&#44; las caracter&#237;sticas de la vivienda y el n&#250;mero de personas que habitan en &#233;sta&#46; Tiene un puntaje de 0 a 12 en el que se considera que a menor puntaje es peor el estrato socioecon&#243;mico&#46;</p><p class="elsevierStylePara elsevierViewall">El AIMS es un cuestionario autoaplicado espec&#237;fico para enfermedades reum&#225;ticas&#46; Se compone de 44 entradas agrupadas en 9 categor&#237;as&#46; Las respuestas se eligen de una escala Likert que va de &#171;nunca&#187; a &#171;siempre&#187; y que califica de 0 a 7 de acuerdo con la direcci&#243;n positiva o negativa de la pregunta&#46; Cada categor&#237;a se promedia con el n&#250;mero de preguntas contestadas y se transforma en base 10&#46; Se considera que a mayor calificaci&#243;n es peor la calidad de vida<a class="elsevierStyleCrossRef" href="#bib10"><span class="elsevierStyleSup">10</span></a>&#46;</p><p class="elsevierStylePara elsevierViewall">El MOS-20 es una variante del cuestionario de salud SF-36&#46; Es un cuestionario autoaplicado de 20 preguntas agrupadas en 6 dimensiones &#40;funci&#243;n f&#237;sica&#44; rol funcional&#44; funci&#243;n social&#44; salud mental&#44; percepci&#243;n de la salud y del dolor&#41;&#46; Las respuestas se eligen de una escala Likert&#46; La calificaci&#243;n de cada categor&#237;a se obtiene con el promedio de las preguntas contestadas&#46; Los valores se ajustan sobre la base del sentido de la pregunta para que las calificaciones mayores indiquen una mejor calidad de vida y se transforman linealmente en un intervalo de 0 a 100<a class="elsevierStyleCrossRefs" href="#bib11"><span class="elsevierStyleSup">11&#44;12</span></a>&#46;</p><p class="elsevierStylePara elsevierViewall">El HAQ-DI es un instrumento gen&#233;rico que mide la capacidad funcional del pacientes en la &#250;ltima semana&#46; Es un cuestionario autoaplicado compuesto de 20 preguntas&#44; que se sintetizan en 8 categor&#237;as&#46; Las respuestas se califican en una escala ordinal con valores de 0 a 3&#46; La calificaci&#243;n global es el promedio de todas las calificaciones&#46; Se considera que a mayor calificaci&#243;n es mayor la discapacidad funcional<a class="elsevierStyleCrossRefs" href="#bib13"><span class="elsevierStyleSup">13&#8211;16</span></a>&#46; Este cuestionario se ha validado recientemente al aplicarse a un grupo de pacientes con gota y ha demostrado ser &#250;til en la medici&#243;n de la capacidad funcional de &#233;stos<a class="elsevierStyleCrossRef" href="#bib8"><span class="elsevierStyleSup">8</span></a>&#46;</p><p class="elsevierStylePara elsevierViewall">Los cuestionarios AIMS&#44; MOS-20 y HAQ-DI se aplicaron en la valoraci&#243;n basal&#46; Para determinar la sensibilidad al cambio&#44; se realiz&#243; una segunda evaluaci&#243;n de los mismos par&#225;metros en 20 pacientes despu&#233;s de 8 semanas&#46; Los cuestionarios se autoaplicaron antes de la valoraci&#243;n m&#233;dica por el reumat&#243;logo aunque siempre estuvo disponible un encuestador entrenado para ayudar a los pacientes que tuvieran dificultades con el llenado&#46; No hubo ning&#250;n criterio de selecci&#243;n para los 20 pacientes que tuvieron una segunda valoraci&#243;n y fueron aquellos que acudieron a la siguiente visita&#46;</p></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">An&#225;lisis estad&#237;stico</span><p class="elsevierStylePara elsevierViewall">Para calcular las medidas de tendencia central y de dispersi&#243;n se utilizaron medias y desviaci&#243;n est&#225;ndar en las variables dimensionales&#44; as&#237; como frecuencias en el caso de las variables nominales y ordinales&#46; La homogeneidad se determin&#243; con el alfa de Cronbach&#44; en la que se consideraron significativos los valores superiores a 0&#44;7 y la estabilidad con el coeficiente de correlaci&#243;n intraclase &#40;CCI&#41; en los pacientes con 2 valoraciones &#40;prueba y reprueba&#41; como medidas de reproducibilidad&#46; Se hicieron correlaciones entre los cuestionarios&#44; el tM&#44; la FP y las variables cl&#237;nicas&#46; Para determinar la sensibilidad al cambio se calcul&#243; la diferencia entre ambas mediciones&#44; es decir&#44; el porcentaje de cambio &#40;&#91;X2&#8722;X1&#47;X1&#93;100&#41;&#44; se consideraron significativos los valores mayores al 20&#37; y la correlaci&#243;n entre ambas mediciones por el coeficiente de correlaci&#243;n de Pearson&#46;</p></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStylePara elsevierViewall">Se estudiaron 49 pacientes con GCT&#44; todos de sexo masculino&#44; la edad promedio fue de 53&#177;12 a&#241;os y con una escolaridad promedio de 5&#44;5&#177;3&#44;3 a&#241;os&#46; El estrato socioecon&#243;mico promedio fue de 7&#44;02&#177;2&#44;1&#46; Cuarenta y cuatro pacientes &#40;90&#37;&#41; refirieron tener al menos una comorbilidad&#44; las m&#225;s frecuentes fueron alcoholismo en 35 pacientes &#40;71&#37;&#41;&#44; tabaquismo en 23 pacientes &#40;47&#37;&#41;&#44; hipertensi&#243;n arterial en 11 pacientes &#40;22&#37;&#41;&#44; nefrolitiasis en 9 pacientes &#40;18&#37;&#41;&#44; diabetes mellitus en 2 pacientes &#40;4&#37;&#41; y hepatopat&#237;as en un pacientes &#40;2&#37;&#41;&#46; No hubo diferencias significativas en la calidad de vida o en la capacidad funcional en relaci&#243;n con la presencia o ausencia de las comorbilidades ni en relaci&#243;n con la escolaridad&#44; estrato socioecon&#243;mico o edad en este grupo de pacientes&#46; El tiempo de evoluci&#243;n promedio de la enfermedad fue de 14&#44;9&#177;8&#44;3 a&#241;os&#46; Treinta pacientes ten&#237;an AD &#40;61&#44;2&#37;&#41;&#44; 21 pacientes ten&#237;an articulaciones con limitaci&#243;n funcional &#40;ALF&#41; en los arcos de movilidad &#40;42&#44;9&#37;&#41; y 6 pacientes presentaron AI &#40;12&#44;2&#37;&#41;&#46; La mediana de AD fue de 3 &#40;rango de 0 a 56&#41; y la mediana de AI de 1 &#40;rango de 0 a 3&#41;&#46; Las principales AD y ALF fueron las rodillas&#44; los tobillos&#44; los codos y las mu&#241;ecas&#46; Los tofos se localizaron principalmente en codos&#44; mu&#241;ecas&#44; metacarpofal&#225;ngicas&#44; interfal&#225;ngicas proximales&#44; rodillas&#44; tobillos y primera metatarsofal&#225;ngica&#46; Todos los pacientes presentaron tofos al momento del estudio&#59; 6 &#40;12&#44;2&#37;&#41; eran de localizaci&#243;n intrad&#233;rmica&#46; La mediana del n&#250;mero de tofos fue de 4 &#40;rango de 1 a 32&#41;&#46;</p><p class="elsevierStylePara elsevierViewall">Las EVA de valoraci&#243;n de dolor y salud global en el pacientes fueron de 24&#44;2&#177;25<span class="elsevierStyleHsp" style=""></span>mm y de 50&#44;9&#177;30<span class="elsevierStyleHsp" style=""></span>mm&#44; respectivamente&#46; La FP promedio de ambas manos fue de 159&#177;62 mmHg&#46; La FP estuvo disminuida de forma significativa entre los pacientes con ALF en ambas manos &#40;p&#61;0&#44;000&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl1">tabla 1</a>&#41;&#46; En los pacientes con dolor en las extremidades superiores &#40;n&#61;16&#41; se encontraron diferencias significativas de la FP al ser comparados con los pacientes sin dolor&#46; En la mano derecha la FP fue de 128&#44;06&#177;78&#44;89<span class="elsevierStyleHsp" style=""></span>mmHg para los pacientes con dolor frente a 174&#44;33&#177;56&#44;95<span class="elsevierStyleHsp" style=""></span>mmHg para los pacientes sin dolor &#40;p&#61;0&#44;023&#41;&#59; en la mano izquierda fue de 131&#44;44&#177;65&#44;73<span class="elsevierStyleHsp" style=""></span>mmHg para los pacientes con dolor frente a 171&#44;30&#177;56<span class="elsevierStyleHsp" style=""></span>mmHg para los pacientes sin dolor &#40;p&#61;0&#44;032&#41;&#46; La FP se correlacion&#243; con la presencia de ALF &#40;r&#61;&#8722;0&#44;6&#59; p&#61;0&#44;000&#41; y con la EVA de dolor &#40;r&#61;&#8722;0&#44;328&#59; p&#61;0&#44;022&#41;&#46; La correlaci&#243;n de la FP entre ambas manos fue de 0&#44;83 &#40;p&#61;0&#44;000&#41;&#46;</p><elsevierMultimedia ident="tbl1"></elsevierMultimedia><p class="elsevierStylePara elsevierViewall">El tM promedio de 15 m fue de 0&#44;14&#177;0&#44;05 min&#46; El tM fue mayor en los pacientes con AD &#40;0&#44;16&#177;0&#44;65<span class="elsevierStyleHsp" style=""></span>min&#41; que en los pacientes sin dolor articular &#40;0&#44;12&#177;0&#44;02<span class="elsevierStyleHsp" style=""></span>min&#41; &#40;p&#61;0&#44;022&#41;&#46; Tambi&#233;n se encontr&#243; una diferencia significativa del tM entre los pacientes con ALF y sin ALF &#40;0&#44;17&#177;0&#44;07<span class="elsevierStyleHsp" style=""></span>min frente a 0&#44;13&#177;0&#44;03<span class="elsevierStyleHsp" style=""></span>min&#44; respectivamente&#59; p&#61;0&#44;004&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46; Los pacientes con dolor en las extremidades inferiores &#40;n&#61;21&#41; tuvieron mayor tM que los pacientes sin dolor&#58; 0&#44;17&#177;0&#44;07<span class="elsevierStyleHsp" style=""></span>min frente a 0&#44;12&#177;0&#44;02<span class="elsevierStyleHsp" style=""></span>min &#40;p&#61;0&#44;001&#41;&#46; El tM s&#243;lo se correlacion&#243; con la presencia de AD &#40;r&#61;0&#44;3&#59; p&#61;0&#44;042&#41;&#46; No hubo diferencias significativas entre los pacientes con inflamaci&#243;n articular y sin inflamaci&#243;n articular&#46;</p><elsevierMultimedia ident="tbl2"></elsevierMultimedia><p class="elsevierStylePara elsevierViewall">A continuaci&#243;n se presentan los resultados por cada instrumento en relaci&#243;n con la capacidad funcional y la calidad de vida&#46;</p><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Escala de medici&#243;n del impacto de la artritis</span><p class="elsevierStylePara elsevierViewall">Las categor&#237;as m&#225;s afectadas fueron el dolor&#44; la actividad social&#44; la actividad f&#237;sica y la movilidad &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46; En los pacientes con AD la movilidad&#44; el desempe&#241;o social&#44; las actividades cotidianas y el dolor tuvieron calificaciones significativamente mayores que en aqu&#233;llos sin dolor&#46; En los pacientes con ALF&#44; las categor&#237;as de actividad f&#237;sica&#44; destreza&#44; desempe&#241;o social y dolor tuvieron calificaciones significativamente mayores &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46;</p></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Resultados m&#233;dicos del formulario corto del estudio de la encuesta de salud</span><p class="elsevierStylePara elsevierViewall">Las categor&#237;as m&#225;s afectadas fueron el dolor y la percepci&#243;n de la salud &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46; En los pacientes con AD&#44; las categor&#237;as de dolor y funci&#243;n social tuvieron calificaciones significativamente menores en comparaci&#243;n con los pacientes sin dolor&#46; En los pacientes con ALF&#44; el rol funcional&#44; la funci&#243;n social y el dolor tuvieron calificaciones significativamente menores &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46;</p></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Cuestionario de evaluaci&#243;n de salud</span><p class="elsevierStylePara elsevierViewall">Este instrumento se emple&#243; para validar la convergencia de los otros 2 cuestionarios&#46; Las calificaciones promedio del HAQ-DI estuvieron por debajo de uno en todas las categor&#237;as&#44; las m&#225;s afectadas fueron el levantarse&#44; la higiene&#44; las actividades&#44; y el sujetar y alcanzar cosas&#46; La media de la calificaci&#243;n del HAQ-DI fue de 0&#44;43&#177;0&#44;56 &#40;intervalo de confianza &#91;IC&#93; del 95&#37;&#44; rango de 0&#44;27 a 0&#44;60&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46; En los pacientes que ten&#237;an ALF&#44; el HAQ-DI fue de 0&#44;74&#177;0&#44;61&#46; En los pacientes sin ALF&#44; el HAQ-DI fue de 0&#44;18&#177;0&#44;37 &#40;p&#61;0&#44;000&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl2">tabla 2</a>&#41;&#46;</p></span></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Correlaciones de los cuestionarios</span><p class="elsevierStylePara elsevierViewall">El HAQ-DI se correlacion&#243; con la FP de ambas manos &#40;r&#61;&#8722;0&#44;6&#59; p&#61;0&#44;000 en ambas&#41;&#44; la ALF &#40;r&#61;0&#44;6&#59; p&#61;0&#44;000&#41; y la EVA de dolor &#40;r&#61;0&#44;6&#59; p&#61;0&#44;000&#41;&#46; Asimismo&#44; se correlacion&#243; con las categor&#237;as del AIMS de movilidad &#40;r&#61;0&#44;6&#59; p&#61;0&#44;000&#41;&#44; actividad f&#237;sica &#40;r&#61;0&#44;4&#59; p&#61;0&#44;006&#41;&#44; destreza &#40;r&#61;0&#44;4&#59; p&#61;0&#44;011&#41;&#44; desempe&#241;o social &#40;r&#61;0&#44;5&#59; p&#61;0&#44;000&#41;&#44; actividad social &#40;r&#61;0&#44;4&#59; p&#61;0&#44;010&#41;&#44; actividades cotidianas &#40;r&#61;0&#44;4&#59; p&#61;0&#44;006&#41; y dolor &#40;r&#61;0&#44;4&#59; p&#61;0&#44;020&#41;&#44; pero no con depresi&#243;n &#40;r&#61;0&#44;3&#59; p&#61;0&#44;072&#41; o ansiedad &#40;r&#61;0&#44;1&#59; p&#61;0&#44;45&#41;&#46; Se correlacion&#243; con el MOS-20 en las dimensiones de funci&#243;n f&#237;sica &#40;r&#61;&#8722;0&#44;5&#59; p&#61;0&#44;000&#41;&#44; rol funcional &#40;r&#61;&#8722;0&#44;5&#59; p&#61;0&#44;001&#41;&#44; funci&#243;n social &#40;r&#61;&#8722;0&#44;5&#59; p&#61;0&#44;001&#41;&#44; percepci&#243;n de la salud &#40;r&#61;&#8722;0&#44;3&#59; p&#61;0&#44;021&#41; y dolor &#40;r&#61;&#8722;0&#44;3&#59; p&#61;0&#44;035&#41;&#44; pero no se correlacion&#243; con la salud mental &#40;r&#61;&#8722;0&#44;1&#59; p&#61;0&#44;38&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl4">tabla 4</a>&#41;&#46;</p></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Sensibilidad al cambio</span><p class="elsevierStylePara elsevierViewall">Se obtuvo una segunda medici&#243;n de los instrumentos en s&#243;lo 20 pacientes que acudieron a una segunda valoraci&#243;n despu&#233;s de 8 semanas de la visita basal&#46; No hubo diferencias significativas en las variables demogr&#225;ficas o cl&#237;nicas entre los pacientes que acudieron a la segunda visita en comparaci&#243;n con aquellos pacientes que no acudieron&#46; Tampoco hubo diferencias en la medici&#243;n basal ni en la medici&#243;n final en el grupo total&#44; debido a que la mayor&#237;a de los pacientes se encontraba en per&#237;odo intercr&#237;tico&#46; Al comparar la primera con la segunda medici&#243;n se encontraron porcentajes de cambio mayores al 20&#37; en las categor&#237;as de destreza&#44; desempe&#241;o social&#44; actividades cotidianas&#44; dolor y depresi&#243;n del AIMS y en las dimensiones de funci&#243;n f&#237;sica&#44; funci&#243;n social&#44; percepci&#243;n de la salud &#40;salud global&#41; y dolor del MOS-20&#46; En la prueba y en la reprueba se observaron mejores puntajes del CCI en los componentes de movilidad&#44; actividad f&#237;sica y destreza del AIMS y en los de funci&#243;n f&#237;sica&#44; rol funcional y dolor del MOS-20&#46; S&#243;lo se encontraron correlaciones significativas entre la primera y la segunda valoraci&#243;n en los componentes de movilidad y destreza del AIMS&#44; la salud mental del MOS-20 y en el HAQ-DI &#40;<a class="elsevierStyleCrossRefs" href="#tbl3">tablas 3 y 4</a>&#41;&#46;</p><elsevierMultimedia ident="tbl3"></elsevierMultimedia><elsevierMultimedia ident="tbl4"></elsevierMultimedia></span><span class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Discusi&#243;n</span><p class="elsevierStylePara elsevierViewall">En el presente estudio se aplicaron los cuestionarios AIMS y MOS-20 a pacientes con gota&#59; los cuestionarios demostraron tener una buena reproducibilidad as&#237; como moderada sensibilidad al cambio para la medici&#243;n de la capacidad funcional y de la calidad de vida&#46;</p><p class="elsevierStylePara elsevierViewall">El AIMS tuvo una reproducibilidad &#40;&#945; de Cronbach de 0&#44;66 a 0&#44;96 entre los diferentes componentes&#41;&#44; similar a la reportada para pacientes con artritis reumatoide &#40;AR&#41; &#40;de 0&#44;71 a 0&#44;93&#41;&#46; Las categor&#237;as m&#225;s afectadas fueron el dolor &#40;5&#44;94&#177;1&#44;88&#41;&#44; la actividad social &#40;5&#44;76&#177;1&#44;92&#41; &#40;es posible que la presencia de tofos sea la causa de este fen&#243;meno&#41;&#44; la actividad f&#237;sica &#40;4&#44;44&#177;1&#44;93&#41; y la movilidad &#40;4&#44;30&#177;1&#44;81&#41;&#46; Por otra parte&#44; las categor&#237;as menos afectadas fueron las actividades cotidianas &#40;2&#44;66&#177;2&#44;20&#41;&#44; el desempe&#241;o social &#40;2&#44;67&#177;1&#44;60&#41; y la destreza &#40;2&#44;68&#177;1&#44;68&#41;&#46; La mayor&#237;a de las calificaciones fueron similares a las reportadas en los pacientes con AR<a class="elsevierStyleCrossRef" href="#bib10"><span class="elsevierStyleSup">10</span></a>&#44; con excepci&#243;n de la destreza&#44; la depresi&#243;n y la ansiedad que est&#225;n m&#225;s afectadas en los pacientes con AR&#44; mientras que la actividad social se ve m&#225;s afectada en los pacientes con gota&#46;</p><p class="elsevierStylePara elsevierViewall">Se encontr&#243; una correlaci&#243;n divergente&#44; de moderada a buena&#44; entre las categor&#237;as de movilidad&#44; actividad f&#237;sica y destreza del AIMS&#44; con la funci&#243;n f&#237;sica y el rol funcional del MOS-20&#46; La salud mental y la funci&#243;n social del MOS-20 se correlacionaron con situaciones de depresi&#243;n y ansiedad reflejadas en el AIMS&#46; Las categor&#237;as de dolor de ambos instrumentos tuvieron una correlaci&#243;n significativa&#46; Las calificaciones de movilidad&#44; actividad f&#237;sica&#44; destreza&#44; desempe&#241;o social y dolor fueron significativamente mayores en los pacientes con ALF&#46; Todas las mediciones del MOS-20 se encontraron disminuidas en este grupo de pacientes&#44; las m&#225;s afectadas fueron la percepci&#243;n de la salud &#40;34&#44;26&#177;16&#44;55&#41; y el dolor &#40;37&#44;23&#177;34&#44;53&#41;&#44; y la menos afectada fue la salud mental &#40;70&#44;33&#177;21&#44;59&#41;&#46; La misma tendencia se observa al hacer la medici&#243;n de la calidad de vida con SF-36&#44; en el que hay mayor afecci&#243;n del componente f&#237;sico que del componente mental<a class="elsevierStyleCrossRef" href="#bib9"><span class="elsevierStyleSup">9</span></a>&#46; El rol funcional&#44; la funci&#243;n f&#237;sica y el dolor se encontraron significativamente menores en los pacientes con ALF&#46; La presencia de afecci&#243;n en las extremidades superiores disminuy&#243; la FP&#44; mientras que la afecci&#243;n en las extremidades inferiores prolong&#243; el tM&#46;</p><p class="elsevierStylePara elsevierViewall">El HAQ-DI tuvo una correlaci&#243;n significativa con la EVA de dolor&#44; el tM&#44; la FP&#44; la presencia de ALF y con los dominios relacionados con la funci&#243;n f&#237;sica m&#225;s que con los de salud mental del AIMS y del MOS-20&#46; Esto concuerda con lo reportado previamente&#44; es decir&#44; hay una mejor correlaci&#243;n del HAQ-DI con los componentes de funci&#243;n f&#237;sica as&#237; como una correlaci&#243;n baja con los componentes de salud mental del cuestionario de salud SF-36<a class="elsevierStyleCrossRef" href="#bib8"><span class="elsevierStyleSup">8</span></a>&#46; Debido a que en este estudio s&#243;lo se incluyeron pacientes con GCT y a que la mayor&#237;a se encontraba en per&#237;odo intercr&#237;tico&#44; no se encontraron diferencias significativas con relaci&#243;n a la presencia de tofos y AI como en otros trabajos que han incluido pacientes con un espectro m&#225;s amplio de la enfermedad<a class="elsevierStyleCrossRefs" href="#bib5"><span class="elsevierStyleSup">5&#8211;8</span></a>&#46; En un estudio de 375 pacientes con gota&#44; de los cuales el 62&#37; ten&#237;a tofos&#44; se encontr&#243; que en los pacientes con 5 o m&#225;s tofos la calificaci&#243;n del HAQ-DI era significativamente mayor cuando se la comparaba con los que ten&#237;an menos de 5 tofos &#40;0&#44;38&#177;0&#44;84 frente a 0&#44;04&#177;0&#44;15&#59; p&#61;0&#44;000&#41;<a class="elsevierStyleCrossRef" href="#bib5"><span class="elsevierStyleSup">5</span></a>&#46; &#193;lvarez-Hern&#225;ndez et al encontraron una tendencia similar en un estudio multic&#233;ntrico que incluy&#243; 206 pacientes&#44; de los cuales el 37&#37; ten&#237;a tofos&#46; En los pacientes con tofos el HAQ-DI fue de 1&#44;01&#177;0&#44;84&#44; mientras que en los pacientes sin tofos fue de 0&#44;35&#177;0&#44;56 &#40;p&#61;0&#44;000&#41;<a class="elsevierStyleCrossRef" href="#bib8"><span class="elsevierStyleSup">8</span></a>&#46; &#193;lvarez-Nemegyei tambi&#233;n reporta la presencia de tofos como un factor de riesgo para la presencia de discapacidad musculoesquel&#233;tica &#40;DME&#41; con un riesgo relativo de 4&#44;3 &#40;IC del 95&#37;&#44; rango de 1&#44;2 a 15&#44;1&#41;&#46; Asimismo&#44; tambi&#233;n reporta una diferencia significativa de la calificaci&#243;n del HAQ-DI entre los pacientes con DME comparados con aquellos pacientes sin DME &#40;0&#44;17&#177;0&#44;21 frente a 0&#44;02&#177;0&#44;0004&#59; p&#61;0&#44;000&#41;<a class="elsevierStyleCrossRef" href="#bib7"><span class="elsevierStyleSup">7</span></a>&#46; &#201;sta es una situaci&#243;n similar a la que se encuentra en este trabajo entre los pacientes con ALF y sin ALF &#40;0&#44;74&#177;0&#44;61 frente a 0&#44;18&#177;0&#44;37&#59; p&#61;0&#44;000&#41;&#46;</p><p class="elsevierStylePara elsevierViewall">La sensibilidad al cambio fue mejor en los componentes de funci&#243;n f&#237;sica del AIMS y del MOS-20&#44; pero fue pobre en los componentes de salud mental&#46;</p><p class="elsevierStylePara elsevierViewall">Una de las principales limitaciones del estudio es que s&#243;lo se incluyeron los pacientes con GCT en per&#237;odo intercr&#237;tico&#46; Debido a esta restricci&#243;n no fue posible realizar comparaciones con pacientes que tuvieran ataque agudo o con pacientes sin la presencia de tofos&#44; lo que posibilitar&#237;a tener un espectro m&#225;s amplio y verificar si estos instrumentos tienen diferencias significativas entre los subgrupos de pacientes&#46;</p><p class="elsevierStylePara elsevierViewall">Este estudio concluye que el AIMS y el MOS-20 pueden ser &#250;tiles en la valoraci&#243;n de la capacidad funcional y de la calidad de vida de los pacientes con gota&#44; tanto en la pr&#225;ctica cl&#237;nica como en estudios de investigaci&#243;n&#46;</p></span></span>"
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          "identificador" => "xres125482"
          "titulo" => array:6 [
            0 => "Resumen"
            1 => "Introducci&#243;n"
            2 => "Objetivo"
            3 => "Pacientes y m&#233;todos"
            4 => "Resultados"
            5 => "Conclusi&#243;n"
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          "identificador" => "xpalclavsec112776"
          "titulo" => "Palabras clave"
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        2 => array:2 [
          "identificador" => "xres125483"
          "titulo" => array:6 [
            0 => "Abstract"
            1 => "Introduction"
            2 => "Objective"
            3 => "Methods"
            4 => "Results"
            5 => "Conclusion"
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        3 => array:2 [
          "identificador" => "xpalclavsec112775"
          "titulo" => "Keywords"
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        4 => array:1 [
          "titulo" => "Introducci&#243;n"
        ]
        5 => array:1 [
          "titulo" => "Pacientes y m&#233;todos"
        ]
        6 => array:1 [
          "titulo" => "An&#225;lisis estad&#237;stico"
        ]
        7 => array:2 [
          "titulo" => "Resultados"
          "secciones" => array:3 [
            0 => array:1 [
              "titulo" => "Escala de medici&#243;n del impacto de la artritis"
            ]
            1 => array:1 [
              "titulo" => "Resultados m&#233;dicos del formulario corto del estudio de la encuesta de salud"
            ]
            2 => array:1 [
              "titulo" => "Cuestionario de evaluaci&#243;n de salud"
            ]
          ]
        ]
        8 => array:1 [
          "titulo" => "Correlaciones de los cuestionarios"
        ]
        9 => array:1 [
          "titulo" => "Sensibilidad al cambio"
        ]
        10 => array:1 [
          "titulo" => "Discusi&#243;n"
        ]
        11 => array:1 [
          "titulo" => "Bibliograf&#237;a"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2008-05-27"
    "fechaAceptado" => "2008-11-27"
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec112776"
          "palabras" => array:3 [
            0 => "Gota cr&#243;nica tof&#225;cea"
            1 => "Calidad de vida relacionada con la salud"
            2 => "Capacidad funcional"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec112775"
          "palabras" => array:3 [
            0 => "Tophaceus gout"
            1 => "Health-related quality of life"
            2 => "Functional capacity"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">Hay pocos instrumentos en el estudio de gota validados para evaluar la actividad&#44; la capacidad funcional o la calidad de vida de los pacientes&#46; Se desconoce si los instrumentos gen&#233;ricos como el cuestionario MOS-20 &#40;Medical Outcomes Study Short Form Health Survey &#8216;Resultados m&#233;dicos del formulario corto del estudio de la encuesta de salud&#8217;&#41; o los instrumentos espec&#237;ficos para otras enfermedades&#44; como el cuestionario AIMS &#40;Arthritis Impact Measurement Scales &#8216;Escala de medici&#243;n del impacto de la artritis&#8217;&#41; puedan aplicarse a pacientes con gota&#46;</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Evaluar las caracter&#237;sticas clinim&#233;tricas de los cuestionarios MOS-20 y AIMS y su correlaci&#243;n con el cuestionario HAQ-DI &#40;Health Assessment Questionnaire &#8216;Cuestionario de evaluaci&#243;n de salud&#8217;&#41; as&#237; como con variables cl&#237;nicas en los pacientes con gota cr&#243;nica tof&#225;cea &#40;GCT&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se incluyeron 49 pacientes con GCT&#46; Se obtuvieron las variables demogr&#225;ficas y cl&#237;nicas&#46; Se aplicaron los 3 cuestionarios en la valoraci&#243;n basal&#46; En 20 pacientes se realiz&#243; una segunda evaluaci&#243;n despu&#233;s de 8 semanas&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Todos los pacientes fueron de sexo masculino&#46; El tiempo de evoluci&#243;n de la enfermedad fue de 14&#44;9&#177;8&#44;3 a&#241;os&#46; El HAQ-DI fue de 0&#44;43&#177;0&#44;56 con un alfa de Cronbach &#40;&#945;C&#41; de 0&#44;95 y un coeficiente de correlaci&#243;n intraclase &#40;CCI&#41; de 0&#44;86&#46; El MOS-20 tuvo un &#945;C de 0&#44;68 a 1&#44;0 y un CCI de 0&#44;27 a 0&#44;61 entre las diferentes dimensiones&#46; El AIMS tuvo un &#945;C de 0&#44;66 a 0&#44;96 y un CCI de 0&#44;11 a 0&#44;79 entre los diferentes componentes&#46; La reproducibilidad fue mejor en los componentes f&#237;sicos que en los componentes de salud mental tanto del MOS-20 como del AIMS&#46; Los cuestionarios MOS-20&#44; AIMS y HAQ-DI correlacionaron con la presencia de articulaciones con limitaci&#243;n funcional&#46; No se encontraron diferencias significativas entre los pacientes con articulaciones inflamadas ni con tofos&#46; El HAQ-DI se correlacion&#243; mejor con las variables del componente f&#237;sico que con las del componente mental de los cuestionarios AIMS y MOS-20&#46;</p> <span class="elsevierStyleSectionTitle">Conclusi&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">Los cuestionarios AIMS&#44; MOS-20 y HAQ-DI son &#250;tiles para valorar la capacidad funcional y la calidad de vida en los pacientes con GCT&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">In gout there are few instruments validated for the evaluation of activity&#44; functional capacity or quality of life&#46; It is not known if generic instruments such as the MOS-20&#44; or specific for other illnesses&#44; such as the AIMS&#44; can be applied to patients with Gout&#46;</p> <span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To evaluate the clinimetric characteristic of the MOS-20 and AIMS questionnaires&#44; and their correlation with HAQ-DI&#44; as well as with clinical variables in patient with tophaceous gout &#40;TG&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p class="elsevierStyleSimplePara elsevierViewall">49 patients with TG were included&#46; Demographic and clinical variables were obtained&#46; The 3 questionnaires were applied at the basal evaluation&#46; A second evaluation was applied to 20 patients&#44; 8 weeks later&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">All patients were male&#46; The time of since onset of the illness was 14&#46;9&#177;8&#46;3 years&#46; The HAQ-DI was 0&#46;43&#177;0&#46;56 with an alpha of Cronbach &#40;&#945;C&#41; of 0&#46;95 and the intraclass correlation coefficient &#40;ICC&#41; was 0&#46;86&#46; The MOS-20 had an &#945;C of 0&#46;68 to 1&#46;0 and a ICC of 0&#46;27 to 0&#46;61 between the several components&#46; The AIMS had an &#945;C of 0&#46;66 to 0&#46;96&#44; and a ICC of 0&#46;11 to 0&#46;79 between the several components&#46; Reliability was better between the physical components in MOS-20 and AIMS&#46; The MOS-20&#44; AIMS and the HAQ-DI correlated with the presence of joints with functional limitation&#46; There weren&#8217;t any significant differences among the patients with inflamed joints&#44; nor in those with tophi&#46; The HAQ-DI was best correlated with the physical component than with the mental component of the AIMS and the MOS-20&#46;</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p class="elsevierStyleSimplePara elsevierViewall">The AIMS&#44; the MOS-20 and the HAQ-DI are useful in measuring the functional capacity and the quality of life in patient with TG&#46;</p>"
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          "leyenda" => "<p class="elsevierStyleSimplePara elsevierViewall">AIMS&#58; escala de medici&#243;n del impacto de la artritis&#59; ALF&#58; articulaci&#243;n con limitaci&#243;n funcional&#59; DE&#58; desviaci&#243;n est&#225;ndar&#59; FP&#58; fuerza de prensi&#243;n&#59; HAQ-DI&#58; cuestionario de evaluaci&#243;n de salud&#59; MOS-20&#58; resultados m&#233;dicos del formulario corto del estudio de la encuesta de salud&#59; tM&#58; tiempo de marcha&#46;</p>"
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                  \t\t\t\t" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">Con ALF &#40;n &#61; 21&#41;&#44; media &#40;DE&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">Sin ALF &#40;n &#61; 28&#41;&#44; media &#40;DE&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">tM &#40;min&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#44;17 &#40;0&#44;07&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#44;000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">AIMS</span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Movilidad&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;14 &#40;2&#44;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;70 &#40;1&#44;12&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividad f&#237;sica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;41 &#40;1&#44;64&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;74 &#40;1&#44;84&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;002&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Destreza&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;51 &#40;1&#44;96&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;08 &#40;1&#44;16&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;003&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Desempe&#241;o social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;64 &#40;1&#44;85&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;99 &#40;0&#44;93&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividad social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;38 &#40;1&#44;66&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;35 &#40;2&#44;01&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;072&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividades cotidianas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;05 &#40;2&#44;35&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;40 &#40;2&#44;10&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;33&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Dolor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;62 &#40;1&#44;66&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;46 &#40;1&#44;91&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;039&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Depresi&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;88 &#40;2&#44;19&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;85 &#40;2&#44;11&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;96&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Ansiedad&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;36 &#40;1&#44;55&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;19 &#40;1&#44;68&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;73&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">MOS-20</span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Funci&#243;n f&#237;sica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">56&#44;08 &#40;39&#44;80&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">76&#44;79 &#40;32&#44;10&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;052&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Rol funcional&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">37&#44;50 &#40;40&#44;96&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">65&#44;18 &#40;39&#44;87&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;023&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Funci&#243;n social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">48&#44;00 &#40;40&#44;73&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">81&#44;43 &#40;23&#44;05&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Salud mental&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">66&#44;00 &#40;24&#44;02&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">73&#44;43 &#40;19&#44;54&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Percepci&#243;n de la salud&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">29&#44;65 &#40;17&#44;05&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">37&#44;59 &#40;15&#44;65&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Dolor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">23&#44;75 &#40;28&#44;65&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">47&#44;22 &#40;35&#44;58&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;019&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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        "descripcion" => array:1 [
          "es" => "<p class="elsevierStyleSimplePara elsevierViewall">Diferencias de las mediciones entre pacientes con articulaciones y sin articulaciones con limitaci&#243;n funcional</p>"
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          "leyenda" => "<p class="elsevierStyleSimplePara elsevierViewall">AIMS&#58; escala de medici&#243;n del impacto de la artritis&#59; DE&#58; desviaci&#243;n est&#225;ndar&#59; HAQ-DI&#58; cuestionario de evaluaci&#243;n de salud&#59; MOS-20&#58; resultados m&#233;dicos del formulario corto del estudio de la encuesta de salud&#46;</p>"
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                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Instrumento&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Media &#40;DE&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Rango&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Alfa de Cronbach&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">AIMS</span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Movilidad&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;30 &#40;1&#44;81&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;9&#44;29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;67&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividad f&#237;sica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;44 &#40;1&#44;93&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;8&#44;29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;66&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Destreza&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;68 &#40;1&#44;68&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;8&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;83&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Desempe&#241;o social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;67 &#40;1&#44;60&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;7&#44;34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;76&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividad social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;76 &#40;1&#44;92&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;75&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividades cotidianas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;66 &#40;2&#44;20&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;96&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Dolor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;94 &#40;1&#44;88&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;14&#8211;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;77&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Depresi&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;86 &#40;2&#44;12&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;9&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;91&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Ansiedad&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;26 &#40;1&#44;62&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;43&#8211;7&#44;14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;73&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">MOS-20</span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Funci&#243;n f&#237;sica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">68&#44;16 &#40;36&#44;59&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#8211;100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;96&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Rol funcional&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">53&#44;65 &#40;42&#44;21&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#8211;100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;97&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Funci&#243;n social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">67&#44;50 &#40;35&#44;40&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#8211;100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Salud mental&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">70&#44;33 &#40;21&#44;59&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">24&#8211;100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;68&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Percepci&#243;n de la salud&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">34&#44;26 &#40;16&#44;55&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#8211;65&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;81&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Dolor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">37&#44;23 &#40;34&#44;53&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#8211;100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HAQ-DI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;43 &#40;0&#44;56&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#8211;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;95&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
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                0 => "xTab212017.png"
              ]
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        ]
        "descripcion" => array:1 [
          "es" => "<p class="elsevierStyleSimplePara elsevierViewall">Consistencia interna de los cuestionarios en 49 pacientes con gota cr&#243;nica tof&#225;cea</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "tbl3"
        "etiqueta" => "Tabla 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
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        "tabla" => array:3 [
          "leyenda" => "<p class="elsevierStyleSimplePara elsevierViewall">AIMS&#58; escala de medici&#243;n del impacto de la artritis&#59; CCI&#58; coeficiente de correlaci&#243;n intraclase&#59; DE&#58; desviaci&#243;n est&#225;ndar&#59; HAQ-DI&#58; cuestionario de evaluaci&#243;n de salud&#59; IC&#58; intervalo de confianza&#59; MOS-20&#58; resultados m&#233;dicos del formulario corto del estudio de la encuesta de la salud&#59; NS&#58; no significativo&#46;</p>"
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                0 => """
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                  \t\t\t\t\tvoid\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Instrumento&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Visita basal&#44; media &#40;DE&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Visita final&#44; media &#40;DE&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Porcentaje de cambio &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Coeficiente de correlaci&#243;n de Pearson &#40;r&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">CCI &#40;IC del 95&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HAQ-DI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;61 &#40;0&#44;63&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;65 &#40;0&#44;77&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">16&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;78 &#40;0&#44;000&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;86 &#40;0&#44;65&#8211;0&#44;95&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">AIMS</span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Movilidad&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;6 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;2 &#40;3&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">16&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;63 &#40;0&#44;004&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;70 &#40;0&#44;25&#8211;0&#44;88&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividad f&#237;sica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;7 &#40;1&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;0 &#40;3&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;30 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;66 &#40;0&#44;34&#8211;0&#44;72&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Destreza&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;0 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;2 &#40;2&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;45 &#40;0&#44;045&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;60 &#40;&#8722;0&#44;02&#8211;0&#44;84&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Desempe&#241;o social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;2 &#40;1&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;8 &#40;3&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">64&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;068 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;11 &#40;&#8722;1&#44;25&#8211;0&#44;65&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividad social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;7 &#40;2&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;9 &#40;3&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;34 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;48 &#40;&#8722;0&#44;36&#8211;0&#44;80&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Actividades cotidianas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;9 &#40;2&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;0 &#40;2&#44;0&#41;<a class="elsevierStyleCrossRef" href="#tblfn3a"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">209&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;27 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;41 &#40;&#8722;0&#44;54&#8211;0&#44;77&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Dolor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;3 &#40;2&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;9 &#40;2&#44;3&#41;<a class="elsevierStyleCrossRef" href="#tblfn3a"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;51&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;20 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;33 &#40;&#8722;0&#44;73&#8211;0&#44;74&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Depresi&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;0 &#40;2&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;5 &#40;2&#44;3&#41;<a class="elsevierStyleCrossRef" href="#tblfn3b"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">67&#44;27&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;23 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;38 &#40;&#8722;0&#44;62&#8211;0&#44;76&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Ansiedad&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;4 &#40;1&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;5 &#40;2&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;4&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;13 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;25 &#40;&#8722;0&#44;33&#8211;0&#44;53&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">MOS-20</span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Funci&#243;n f&#237;sica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">0&#44;44 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">0&#44;61 &#40;0&#44;01&#8211;0&#44;85&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Funci&#243;n social&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">58&#44;0 &#40;37&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">75&#44;0 &#40;38&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">31&#44;12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;22 &#40;NS&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">0&#44;37 &#40;&#8722;0&#44;61&#8211;0&#44;75&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Percepci&#243;n de la salud&nbsp;\t\t\t\t\t\t\n
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          "leyenda" => "<p class="elsevierStyleSimplePara elsevierViewall">AC&#58; actividades cotidianas&#59; AF&#58; actividad f&#237;sica&#59; AIMS&#59; escala de medici&#243;n del impacto de la artritis&#59; Ans&#58; ansiedad&#59; AS&#58; actividad social&#59; Dep&#58; depresi&#243;n&#59; Des&#58; destreza&#59; Dol&#58; dolor&#59; DS&#58; desempe&#241;o social&#59; FF&#58; funci&#243;n f&#237;sica&#59; FS&#58; funci&#243;n social&#59; HAQ-DI&#58; cuestionario de evaluaci&#243;n de salud&#59; MOS-20&#58; resultados m&#233;dicos del formulario corto del estudio de la encuesta de salud&#59; Mov&#58; movilidad&#59; RF&#58; rol funcional&#59; SG&#58; percepci&#243;n de la salud&#59; SM&#58; salud mental&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">Todos expresados con el coeficiente de correlaci&#243;n de Pearson &#40;primera l&#237;nea&#41; y p &#40;segunda l&#237;nea&#41;&#46;</p>"
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                  \t\t\t\t" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">AC&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">Dol&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">FF&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">RF&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">FS&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">SM&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">SG&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">Dol&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">HAQ-DI&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  """
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          "es" => "<p class="elsevierStyleSimplePara elsevierViewall">Matriz de correlaci&#243;n de los componentes de los 3 cuestionarios</p>"
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