array:24 [
  "pii" => "S1699258X14002198"
  "issn" => "1699258X"
  "doi" => "10.1016/j.reuma.2014.10.008"
  "estado" => "S300"
  "fechaPublicacion" => "2015-07-01"
  "aid" => "731"
  "copyright" => "Elsevier España, S.L.U.. All rights reserved"
  "copyrightAnyo" => "2014"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "sco"
  "cita" => "Reumatol Clin. 2015;11:255-7"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 3789
    "formatos" => array:3 [
      "EPUB" => 155
      "HTML" => 2583
      "PDF" => 1051
    ]
  ]
  "Traduccion" => array:1 [
    "en" => array:19 [
      "pii" => "S2173574315000787"
      "issn" => "21735743"
      "doi" => "10.1016/j.reumae.2014.10.003"
      "estado" => "S300"
      "fechaPublicacion" => "2015-07-01"
      "aid" => "731"
      "copyright" => "Elsevier España, S.L.U."
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "sco"
      "cita" => "Reumatol Clin. 2015;11:255-7"
      "abierto" => array:3 [
        "ES" => false
        "ES2" => false
        "LATM" => false
      ]
      "gratuito" => false
      "lecturas" => array:2 [
        "total" => 1675
        "formatos" => array:3 [
          "EPUB" => 52
          "HTML" => 1389
          "PDF" => 234
        ]
      ]
      "en" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Images in Clinical Rheumatology</span>"
        "titulo" => "Hypertrophic osteoarthropathy as a complication of pulmonary tuberculosis"
        "tienePdf" => "en"
        "tieneTextoCompleto" => "en"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "255"
            "paginaFinal" => "257"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "es" => array:1 [
            "titulo" => "Osteoartropat&#237;a hipertr&#243;fica como complicaci&#243;n de la tuberculosis pulmonar"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "en" => true
        ]
        "contienePdf" => array:1 [
          "en" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0015"
            "etiqueta" => "Fig&#46; 3"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr3.jpeg"
                "Alto" => 1314
                "Ancho" => 3001
                "Tamanyo" => 336574
              ]
            ]
            "descripcion" => array:1 [
              "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Radiographs of wrists &#40;A and B&#41; and legs &#40;C&#41; showing periostosis &#40;arrows&#41; at metacarpals&#44; distal ends of the radius&#44; ulna&#44; tibia and fibula&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Mu&#241;oz Carlos Horacio, V&#225;squez Gloria Mar&#237;a, Gonz&#225;lez Luis Alonso"
            "autores" => array:3 [
              0 => array:2 [
                "nombre" => "Mu&#241;oz Carlos"
                "apellidos" => "Horacio"
              ]
              1 => array:2 [
                "nombre" => "V&#225;squez Gloria"
                "apellidos" => "Mar&#237;a"
              ]
              2 => array:2 [
                "nombre" => "Gonz&#225;lez Luis"
                "apellidos" => "Alonso"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "en"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1699258X14002198"
          "doi" => "10.1016/j.reuma.2014.10.008"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X14002198?idApp=UINPBA00004M"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574315000787?idApp=UINPBA00004M"
      "url" => "/21735743/0000001100000004/v1_201507020119/S2173574315000787/v1_201507020119/en/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1699258X14002228"
    "issn" => "1699258X"
    "doi" => "10.1016/j.reuma.2014.10.011"
    "estado" => "S300"
    "fechaPublicacion" => "2015-07-01"
    "aid" => "734"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46;"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "sco"
    "cita" => "Reumatol Clin. 2015;11:258-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2838
      "formatos" => array:3 [
        "EPUB" => 185
        "HTML" => 1848
        "PDF" => 805
      ]
    ]
    "es" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Reumatolog&#237;a cl&#237;nica en im&#225;genes</span>"
      "titulo" => "Arteritis y seudoaneurisma coronarios en la enfermedad de Beh&#231;et&#58; una causa infrecuente de infarto de miocardio"
      "tienePdf" => "es"
      "tieneTextoCompleto" => "es"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "258"
          "paginaFinal" => "259"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Coronary arteritis and pseudoaneurysm in Beh&#231;et&#39;s disease&#58; A rare cause of myocardial infarction"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figura 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1875
              "Ancho" => 2500
              "Tamanyo" => 499460
            ]
          ]
          "descripcion" => array:1 [
            "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Seudoaneurisma de tronco com&#250;n izquierdo&#46; A&#41; Coronariograf&#237;a izquierda en proyecci&#243;n oblicua anterior derecha caudal&#46; TCI&#58; tronco com&#250;n izquierdo&#59; CX&#58; circunfleja&#59; DA&#58; descendente anterior&#46; La flecha se&#241;ala el cuello del seudoaneurisma&#44; delimitado por las cabezas de flecha&#46; B&#41; Coronariograf&#237;a en proyecci&#243;n oblicua izquierda caudal&#46; C&#41; Visi&#243;n del seudoaneurisma desde la posici&#243;n del cirujano&#46; D&#41; Seudoaneurisma abierto&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Marcos Rodr&#237;guez Esteban, Sara Miranda Montero, Horacio P&#233;rez Hern&#225;ndez, Rafael Llorens Le&#243;n"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Marcos"
              "apellidos" => "Rodr&#237;guez Esteban"
            ]
            1 => array:2 [
              "nombre" => "Sara"
              "apellidos" => "Miranda Montero"
            ]
            2 => array:2 [
              "nombre" => "Horacio"
              "apellidos" => "P&#233;rez Hern&#225;ndez"
            ]
            3 => array:2 [
              "nombre" => "Rafael"
              "apellidos" => "Llorens Le&#243;n"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2173574314001750"
        "doi" => "10.1016/j.reumae.2014.12.001"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => false
          "ES2" => false
          "LATM" => false
        ]
        "gratuito" => false
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574314001750?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X14002228?idApp=UINPBA00004M"
    "url" => "/1699258X/0000001100000004/v1_201506200144/S1699258X14002228/v1_201506200144/es/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1699258X14002150"
    "issn" => "1699258X"
    "doi" => "10.1016/j.reuma.2014.10.004"
    "estado" => "S300"
    "fechaPublicacion" => "2015-07-01"
    "aid" => "727"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46;"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "sco"
    "cita" => "Reumatol Clin. 2015;11:252-4"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 44445
      "formatos" => array:3 [
        "EPUB" => 175
        "HTML" => 42068
        "PDF" => 2202
      ]
    ]
    "es" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Reumatolog&#237;a cl&#237;nica en im&#225;genes</span>"
      "titulo" => "Tumor de c&#233;lulas gigantes de las vainas tendinosas de los dedos de la mano"
      "tienePdf" => "es"
      "tieneTextoCompleto" => "es"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "252"
          "paginaFinal" => "254"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Giant cell tumor of the tendon sheaths of the fingers"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0015"
          "etiqueta" => "Figura 3"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr3.jpeg"
              "Alto" => 1552
              "Ancho" => 1500
              "Tamanyo" => 189148
            ]
          ]
          "descripcion" => array:1 [
            "es" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Cortes axiales de RM&#44; observ&#225;ndose una lesi&#243;n hipointensa en T1 &#40;A&#41; e hiperintensa en T2 &#40;B&#41;&#44; con discreta captaci&#243;n tras la administraci&#243;n de contraste &#40;C&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Luis R&#46; Ramos-Pascua, Omar A&#46; Guerra-&#193;lvarez, Paula Casas-Ramos, Francisco Arias-Mart&#237;n"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Luis R&#46;"
              "apellidos" => "Ramos-Pascua"
            ]
            1 => array:2 [
              "nombre" => "Omar A&#46;"
              "apellidos" => "Guerra-&#193;lvarez"
            ]
            2 => array:2 [
              "nombre" => "Paula"
              "apellidos" => "Casas-Ramos"
            ]
            3 => array:2 [
              "nombre" => "Francisco"
              "apellidos" => "Arias-Mart&#237;n"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2173574314001774"
        "doi" => "10.1016/j.reumae.2014.12.003"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => false
          "ES2" => false
          "LATM" => false
        ]
        "gratuito" => false
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574314001774?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X14002150?idApp=UINPBA00004M"
    "url" => "/1699258X/0000001100000004/v1_201506200144/S1699258X14002150/v1_201506200144/es/main.assets"
  ]
  "en" => array:16 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Images in Clinical Rheumatology</span>"
    "titulo" => "Hypertrophic osteoarthropathy as a complication of pulmonary tuberculosis"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "255"
        "paginaFinal" => "257"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Mu&#241;oz Carlos Horacio, V&#225;squez Gloria Mar&#237;a, Gonz&#225;lez Luis Alonso"
        "autores" => array:3 [
          0 => array:2 [
            "nombre" => "Mu&#241;oz Carlos"
            "apellidos" => "Horacio"
          ]
          1 => array:2 [
            "nombre" => "V&#225;squez Gloria"
            "apellidos" => "Mar&#237;a"
          ]
          2 => array:4 [
            "nombre" => "Gonz&#225;lez Luis"
            "apellidos" => "Alonso"
            "email" => array:1 [
              0 => "lagnvvn68&#64;gmail&#46;com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Division of Rheumatology&#44; School of Medicine&#44; Universidad de Antioquia&#44; Hospital Universitario San Vicente Fundaci&#243;n&#44; Medell&#237;n&#44; Colombia"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Osteoartropat&#237;a hipertr&#243;fica como complicaci&#243;n de la tuberculosis pulmonar"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 788
            "Ancho" => 1800
            "Tamanyo" => 162603
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Radiographs of wrists &#40;A and B&#41; and legs &#40;C&#41; showing periostosis &#40;arrows&#41; at metacarpals&#44; distal ends of the radius&#44; ulna&#44; tibia and fibula&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The patient is a 17-year-old man with a history of pulmonary tuberculosis treated for 6 months with the standard regimen &#91;isoniazid&#44; rifampin&#44; ethambutol&#44; and pyrazinamide for 2 months &#40;intensive phase&#41; followed by isoniazid and rifampin for 4 months &#40;continuation phase&#41;&#93; with complete adherence and whose sputum smears at the end of his treatment were negative for acid-fast bacillus&#46; Six months later&#44; he presented to the emergency room complaining of pain and swelling of the ankles&#44; knees and wrists for four weeks prior to admission with no constitutional &#40;fever&#44; night sweats&#44; fatigue&#44; weight loss&#41; and respiratory symptoms&#46; On physical examination&#44; finger clubbing was evident and confirmed by observation of the Schamroth&#39;s sign &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Chest computer tomography showed cystic bronchiectasis and cavitations in the left lower and upper lobes &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; X-rays of wrists and legs showed periosteal reaction along the metacarpals&#44; distal radius&#44; ulna&#44; tibia and fibula &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41; but not acro-osteolysis of the distal phalanges of the hands and feet&#46; Human immunodeficiency virus antibody test was negative&#46; Pharmacologic therapy with nonsteroidal anti-inflammatory drugs was effective in relieving pain from hypertrophic osteoarthropathy &#40;HOA&#41; during his hospital stay and after 3 months of follow-up&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Discussion</span><p id="par0015" class="elsevierStylePara elsevierViewall">HOA is a syndrome characterized by digital clubbing&#44; periostosis of tubular bones and noninflammatory arthritis of large joints&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a> Digital clubbing is characterized by an increase of the normal 160-degree angle between the nail bed and the proximal nail-fold &#40;Lovibond&#39;s angle&#41;&#46; In clubbing&#44; this angle exceeds 180 degrees&#44; while in pseudoclubbing it is preserved&#46; Contrary to digital clubbing&#44; finger involvement is asymmetrical in the majority of the reported cases of pseudoclubbing&#44; and acro-osteolysis instead of an overgrowth of the phalangeal tufts seen in clubbing&#44; is the typical radiographic finding in pseudoclubbing&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">HOA is classified as either primary &#40;pachydermoperiostosis&#41; or secondary to pulmonary&#44; cardiac&#44; liver or gastrointestinal diseases characterized by arteriovenous shunt&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a> Pulmonary malignancies are the most common disorders associated with HOA &#40;80&#37;&#41;&#46; Chronic infections associated with cystic fibrosis&#44; subacute bacterial endocarditis&#44; acquired immunodeficiency syndrome and pulmonary tuberculosis are also associated with HOA&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> Our case illustrates the HOA as a rare late complication of pulmonary tuberculosis&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">The pathogenesis of HOA is unknown&#44; although an impaired lung function due to the exclusion of this organ from part of the circulation is common in most diseases associated with HOA&#46; It has been suggested that in hypoxic conditions&#44; megakaryocytes bypass the pulmonary circulation through arteriovenous shunts and directly reach the distal sites in the systemic circulation and interact with endothelial cells&#44; releasing growth factors&#44; such as vascular endothelial growth factor &#40;VEGF&#41;&#44; resulting in angiogenesis and thus digital clubbing&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;5&#8211;8</span></a> VEGF is a platelet-derived factor induced by hypoxia that produces vascular hyperplasia&#44; new bone formation&#44; edema&#44; and fibroblast&#47;osteoblast proliferation&#44; which are histological alterations of HOA&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">6&#8211;8</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Although the association of HOA with pulmonary tuberculosis has been rarely reported&#44;<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">9&#8211;12</span></a> physicians should consider HOA as a complication of non-neoplastic diseases&#44; such as pulmonary tuberculosis&#44; an endemic infection of the world&#39;s population&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Ethical disclosures</span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Protection of human and animal subjects</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Confidentiality of data</span><p id="par0045" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Right to privacy and informed consent</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors have obtained the written informed consent of the patients or subjects mentioned in the article&#46; The corresponding author is in possession of this document&#46;</p></span></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Conflicts of interest</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:4 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Discussion"
        ]
        1 => array:3 [
          "identificador" => "sec0015"
          "titulo" => "Ethical disclosures"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0020"
              "titulo" => "Protection of human and animal subjects"
            ]
            1 => array:2 [
              "identificador" => "sec0025"
              "titulo" => "Confidentiality of data"
            ]
            2 => array:2 [
              "identificador" => "sec0030"
              "titulo" => "Right to privacy and informed consent"
            ]
          ]
        ]
        2 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Conflicts of interest"
        ]
        3 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2014-05-09"
    "fechaAceptado" => "2014-10-16"
    "multimedia" => array:3 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 642
            "Ancho" => 1301
            "Tamanyo" => 105094
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Digital clubbing&#46; &#40;A&#41; Clubbed appearance of distal phalanges&#46; &#40;B&#41; Positive Schamroth&#39;s sign&#58; the normal diamond-shaped window created by placing the dorsal surfaces of terminal phalanges on opposing fingers together is obliterated in clubbing&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1029
            "Ancho" => 950
            "Tamanyo" => 112166
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Chest computer tomography scan showing cystic bronchiectasis and cavitation in the left lower and upper lobes&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 788
            "Ancho" => 1800
            "Tamanyo" => 162603
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Radiographs of wrists &#40;A and B&#41; and legs &#40;C&#41; showing periostosis &#40;arrows&#41; at metacarpals&#44; distal ends of the radius&#44; ulna&#44; tibia and fibula&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:12 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Digital clubbing and hypertrophic osteoarthropathy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46; Mart&#237;nez-Lav&#237;n"
                            1 => "C&#46; Pineda"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:5 [
                        "titulo" => "Rheumatology"
                        "paginaInicial" => "1701"
                        "paginaFinal" => "1705"
                        "edicion" => "5th ed&#46;"
                        "serieFecha" => "2011"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypertrophic osteoarthropathy&#58; what a rheumatologist should know about this uncommon condition"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Pineda"
                            1 => "M&#46; Mart&#237;nez-Lav&#237;n"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.rdc.2013.02.008"
                      "Revista" => array:6 [
                        "tituloSerie" => "Rheum Dis Clin North Am"
                        "fecha" => "2013"
                        "volumen" => "39"
                        "paginaInicial" => "383"
                        "paginaFinal" => "400"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23597970"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pseudoclubbing&#58; is it different from clubbing&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46;B&#46; Santiago"
                            1 => "I&#46; Lima"
                            2 => "A&#46;C&#46; Feitosa"
                            3 => "S&#46; Braz Ade"
                            4 => "L&#46;G&#46; Miranda"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.semarthrit.2008.01.018"
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Arthritis Rheum"
                        "fecha" => "2009"
                        "volumen" => "38"
                        "paginaInicial" => "452"
                        "paginaFinal" => "457"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18378280"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Periostitis and hypertrophic pulmonary <span class="elsevierStyleItalic">osteoarthropathy</span>&#58; report of 2 cases and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "Q&#46; Yao"
                            1 => "R&#46;D&#46; Altman"
                            2 => "E&#46; Brahn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.semarthrit.2008.07.001"
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Arthritis Rheum"
                        "fecha" => "2009"
                        "volumen" => "38"
                        "paginaInicial" => "458"
                        "paginaFinal" => "466"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18760449"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Megakaryocytes and platelet clumps as the cause of finger clubbing"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46;J&#46; Dickinson"
                            1 => "J&#46;F&#46; Martin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1987"
                        "volumen" => "2"
                        "paginaInicial" => "1434"
                        "paginaFinal" => "1435"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2574367"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Vascular endothelial growth factor &#40;VEGF&#41;-A and platelet-derived growth factor &#40;PDGF&#41; play a central role in the pathogenesis of digital clubbing"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Atkinson"
                            1 => "S&#46;B&#46; Fox"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/path.1565"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Pathol"
                        "fecha" => "2004"
                        "volumen" => "203"
                        "paginaInicial" => "721"
                        "paginaFinal" => "728"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15141388"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Exploring the cause of the most ancient clinical sign of medicine&#58; finger clubbing"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46; Martinez-Lavin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.semarthrit.2006.11.004"
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Arthritis Rheum"
                        "fecha" => "2007"
                        "volumen" => "36"
                        "paginaInicial" => "380"
                        "paginaFinal" => "385"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17276498"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Circulating vascular endothelial growth factor concentrations in a case of pulmonary hypertrophic osteoarthropathy&#46; Correlation with disease activity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Ol&#225;n"
                            1 => "M&#46; Portela"
                            2 => "C&#46; Navarro"
                            3 => "M&#46; Gaxiola"
                            4 => "L&#46;H&#46; Silveira"
                            5 => "V&#46; Ruiz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Rheumatol"
                        "fecha" => "2004"
                        "volumen" => "31"
                        "paginaInicial" => "614"
                        "paginaFinal" => "616"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14994415"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypertrophic osteoarthropathy in association with pulmonary tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "P&#46; Kelly"
                            1 => "P&#46; Manning"
                            2 => "P&#46; Corcoran"
                            3 => "L&#46; Clancy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1991"
                        "volumen" => "99"
                        "paginaInicial" => "769"
                        "paginaFinal" => "770"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1995244"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypertrophic osteoarthropathy associated with pulmonary tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "I&#46; Aissa"
                            1 => "A&#46; Messadi"
                            2 => "S&#46; Boudaya"
                            3 => "F&#46; El Mezni"
                            4 => "T&#46; Kilani"
                            5 => "H&#46; Gh&#233;dira"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.pneumo.2009.11.001"
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Pneumol Clin"
                        "fecha" => "2011"
                        "volumen" => "67"
                        "paginaInicial" => "101"
                        "paginaFinal" => "104"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21497724"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypertrophic osteoarthropathy in pulmonary tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;G&#46; Webb"
                            1 => "P&#46; Thomas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Tubercle"
                        "fecha" => "1986"
                        "volumen" => "67"
                        "paginaInicial" => "225"
                        "paginaFinal" => "228"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3775873"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypertrophic osteoarthropathy&#58; two unusual causes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46;V&#46; Barber"
                            1 => "R&#46; Lechler"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Postgrad Med J"
                        "fecha" => "1983"
                        "volumen" => "59"
                        "paginaInicial" => "254"
                        "paginaFinal" => "255"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6866884"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/1699258X/0000001100000004/v1_201506200144/S1699258X14002198/v1_201506200144/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "33641"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Reumatolog&#237;a Cl&#237;nica en im&#225;gnes"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/1699258X/0000001100000004/v1_201506200144/S1699258X14002198/v1_201506200144/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X14002198?idApp=UINPBA00004M"
]
Compartir
Información de la revista

Estadísticas

Siga este enlace para acceder al texto completo del artículo

Images in Clinical Rheumatology
Hypertrophic osteoarthropathy as a complication of pulmonary tuberculosis
Osteoartropatía hipertrófica como complicación de la tuberculosis pulmonar
Muñoz Carlos Horacio, Vásquez Gloria María, González Luis Alonso
Autor para correspondencia
lagnvvn68@gmail.com

Corresponding author.
Division of Rheumatology, School of Medicine, Universidad de Antioquia, Hospital Universitario San Vicente Fundación, Medellín, Colombia
Leído
11778
Veces
se ha leído el artículo
3209
Total PDF
8569
Total HTML
Compartir estadísticas
 array:24 [
  "pii" => "S1699258X14002198"
  "issn" => "1699258X"
  "doi" => "10.1016/j.reuma.2014.10.008"
  "estado" => "S300"
  "fechaPublicacion" => "2015-07-01"
  "aid" => "731"
  "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46;. All rights reserved"
  "copyrightAnyo" => "2014"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "sco"
  "cita" => "Reumatol Clin. 2015;11:255-7"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 3789
    "formatos" => array:3 [
      "EPUB" => 155
      "HTML" => 2583
      "PDF" => 1051
    ]
  ]
  "Traduccion" => array:1 [
    "en" => array:19 [
      "pii" => "S2173574315000787"
      "issn" => "21735743"
      "doi" => "10.1016/j.reumae.2014.10.003"
      "estado" => "S300"
      "fechaPublicacion" => "2015-07-01"
      "aid" => "731"
      "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46;"
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "sco"
      "cita" => "Reumatol Clin. 2015;11:255-7"
      "abierto" => array:3 [
        "ES" => false
        "ES2" => false
        "LATM" => false
      ]
      "gratuito" => false
      "lecturas" => array:2 [
        "total" => 1675
        "formatos" => array:3 [
          "EPUB" => 52
          "HTML" => 1389
          "PDF" => 234
        ]
      ]
      "en" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Images in Clinical Rheumatology</span>"
        "titulo" => "Hypertrophic osteoarthropathy as a complication of pulmonary tuberculosis"
        "tienePdf" => "en"
        "tieneTextoCompleto" => "en"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "255"
            "paginaFinal" => "257"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "es" => array:1 [
            "titulo" => "Osteoartropat&#237;a hipertr&#243;fica como complicaci&#243;n de la tuberculosis pulmonar"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "en" => true
        ]
        "contienePdf" => array:1 [
          "en" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0015"
            "etiqueta" => "Fig&#46; 3"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr3.jpeg"
                "Alto" => 1314
                "Ancho" => 3001
                "Tamanyo" => 336574
              ]
            ]
            "descripcion" => array:1 [
              "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Radiographs of wrists &#40;A and B&#41; and legs &#40;C&#41; showing periostosis &#40;arrows&#41; at metacarpals&#44; distal ends of the radius&#44; ulna&#44; tibia and fibula&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Mu&#241;oz Carlos Horacio, V&#225;squez Gloria Mar&#237;a, Gonz&#225;lez Luis Alonso"
            "autores" => array:3 [
              0 => array:2 [
                "nombre" => "Mu&#241;oz Carlos"
                "apellidos" => "Horacio"
              ]
              1 => array:2 [
                "nombre" => "V&#225;squez Gloria"
                "apellidos" => "Mar&#237;a"
              ]
              2 => array:2 [
                "nombre" => "Gonz&#225;lez Luis"
                "apellidos" => "Alonso"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "en"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1699258X14002198"
          "doi" => "10.1016/j.reuma.2014.10.008"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X14002198?idApp=UINPBA00004M"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574315000787?idApp=UINPBA00004M"
      "url" => "/21735743/0000001100000004/v1_201507020119/S2173574315000787/v1_201507020119/en/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1699258X14002228"
    "issn" => "1699258X"
    "doi" => "10.1016/j.reuma.2014.10.011"
    "estado" => "S300"
    "fechaPublicacion" => "2015-07-01"
    "aid" => "734"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46;"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "sco"
    "cita" => "Reumatol Clin. 2015;11:258-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2838
      "formatos" => array:3 [
        "EPUB" => 185
        "HTML" => 1848
        "PDF" => 805
      ]
    ]
    "es" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Reumatolog&#237;a cl&#237;nica en im&#225;genes</span>"
      "titulo" => "Arteritis y seudoaneurisma coronarios en la enfermedad de Beh&#231;et&#58; una causa infrecuente de infarto de miocardio"
      "tienePdf" => "es"
      "tieneTextoCompleto" => "es"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "258"
          "paginaFinal" => "259"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Coronary arteritis and pseudoaneurysm in Beh&#231;et&#39;s disease&#58; A rare cause of myocardial infarction"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figura 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1875
              "Ancho" => 2500
              "Tamanyo" => 499460
            ]
          ]
          "descripcion" => array:1 [
            "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Seudoaneurisma de tronco com&#250;n izquierdo&#46; A&#41; Coronariograf&#237;a izquierda en proyecci&#243;n oblicua anterior derecha caudal&#46; TCI&#58; tronco com&#250;n izquierdo&#59; CX&#58; circunfleja&#59; DA&#58; descendente anterior&#46; La flecha se&#241;ala el cuello del seudoaneurisma&#44; delimitado por las cabezas de flecha&#46; B&#41; Coronariograf&#237;a en proyecci&#243;n oblicua izquierda caudal&#46; C&#41; Visi&#243;n del seudoaneurisma desde la posici&#243;n del cirujano&#46; D&#41; Seudoaneurisma abierto&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Marcos Rodr&#237;guez Esteban, Sara Miranda Montero, Horacio P&#233;rez Hern&#225;ndez, Rafael Llorens Le&#243;n"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Marcos"
              "apellidos" => "Rodr&#237;guez Esteban"
            ]
            1 => array:2 [
              "nombre" => "Sara"
              "apellidos" => "Miranda Montero"
            ]
            2 => array:2 [
              "nombre" => "Horacio"
              "apellidos" => "P&#233;rez Hern&#225;ndez"
            ]
            3 => array:2 [
              "nombre" => "Rafael"
              "apellidos" => "Llorens Le&#243;n"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2173574314001750"
        "doi" => "10.1016/j.reumae.2014.12.001"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => false
          "ES2" => false
          "LATM" => false
        ]
        "gratuito" => false
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574314001750?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X14002228?idApp=UINPBA00004M"
    "url" => "/1699258X/0000001100000004/v1_201506200144/S1699258X14002228/v1_201506200144/es/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1699258X14002150"
    "issn" => "1699258X"
    "doi" => "10.1016/j.reuma.2014.10.004"
    "estado" => "S300"
    "fechaPublicacion" => "2015-07-01"
    "aid" => "727"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46;"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "sco"
    "cita" => "Reumatol Clin. 2015;11:252-4"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 44445
      "formatos" => array:3 [
        "EPUB" => 175
        "HTML" => 42068
        "PDF" => 2202
      ]
    ]
    "es" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Reumatolog&#237;a cl&#237;nica en im&#225;genes</span>"
      "titulo" => "Tumor de c&#233;lulas gigantes de las vainas tendinosas de los dedos de la mano"
      "tienePdf" => "es"
      "tieneTextoCompleto" => "es"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "252"
          "paginaFinal" => "254"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Giant cell tumor of the tendon sheaths of the fingers"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0015"
          "etiqueta" => "Figura 3"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr3.jpeg"
              "Alto" => 1552
              "Ancho" => 1500
              "Tamanyo" => 189148
            ]
          ]
          "descripcion" => array:1 [
            "es" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Cortes axiales de RM&#44; observ&#225;ndose una lesi&#243;n hipointensa en T1 &#40;A&#41; e hiperintensa en T2 &#40;B&#41;&#44; con discreta captaci&#243;n tras la administraci&#243;n de contraste &#40;C&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Luis R&#46; Ramos-Pascua, Omar A&#46; Guerra-&#193;lvarez, Paula Casas-Ramos, Francisco Arias-Mart&#237;n"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Luis R&#46;"
              "apellidos" => "Ramos-Pascua"
            ]
            1 => array:2 [
              "nombre" => "Omar A&#46;"
              "apellidos" => "Guerra-&#193;lvarez"
            ]
            2 => array:2 [
              "nombre" => "Paula"
              "apellidos" => "Casas-Ramos"
            ]
            3 => array:2 [
              "nombre" => "Francisco"
              "apellidos" => "Arias-Mart&#237;n"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2173574314001774"
        "doi" => "10.1016/j.reumae.2014.12.003"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => false
          "ES2" => false
          "LATM" => false
        ]
        "gratuito" => false
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574314001774?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X14002150?idApp=UINPBA00004M"
    "url" => "/1699258X/0000001100000004/v1_201506200144/S1699258X14002150/v1_201506200144/es/main.assets"
  ]
  "en" => array:16 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Images in Clinical Rheumatology</span>"
    "titulo" => "Hypertrophic osteoarthropathy as a complication of pulmonary tuberculosis"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "255"
        "paginaFinal" => "257"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Mu&#241;oz Carlos Horacio, V&#225;squez Gloria Mar&#237;a, Gonz&#225;lez Luis Alonso"
        "autores" => array:3 [
          0 => array:2 [
            "nombre" => "Mu&#241;oz Carlos"
            "apellidos" => "Horacio"
          ]
          1 => array:2 [
            "nombre" => "V&#225;squez Gloria"
            "apellidos" => "Mar&#237;a"
          ]
          2 => array:4 [
            "nombre" => "Gonz&#225;lez Luis"
            "apellidos" => "Alonso"
            "email" => array:1 [
              0 => "lagnvvn68&#64;gmail&#46;com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Division of Rheumatology&#44; School of Medicine&#44; Universidad de Antioquia&#44; Hospital Universitario San Vicente Fundaci&#243;n&#44; Medell&#237;n&#44; Colombia"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Osteoartropat&#237;a hipertr&#243;fica como complicaci&#243;n de la tuberculosis pulmonar"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 788
            "Ancho" => 1800
            "Tamanyo" => 162603
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Radiographs of wrists &#40;A and B&#41; and legs &#40;C&#41; showing periostosis &#40;arrows&#41; at metacarpals&#44; distal ends of the radius&#44; ulna&#44; tibia and fibula&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The patient is a 17-year-old man with a history of pulmonary tuberculosis treated for 6 months with the standard regimen &#91;isoniazid&#44; rifampin&#44; ethambutol&#44; and pyrazinamide for 2 months &#40;intensive phase&#41; followed by isoniazid and rifampin for 4 months &#40;continuation phase&#41;&#93; with complete adherence and whose sputum smears at the end of his treatment were negative for acid-fast bacillus&#46; Six months later&#44; he presented to the emergency room complaining of pain and swelling of the ankles&#44; knees and wrists for four weeks prior to admission with no constitutional &#40;fever&#44; night sweats&#44; fatigue&#44; weight loss&#41; and respiratory symptoms&#46; On physical examination&#44; finger clubbing was evident and confirmed by observation of the Schamroth&#39;s sign &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Chest computer tomography showed cystic bronchiectasis and cavitations in the left lower and upper lobes &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; X-rays of wrists and legs showed periosteal reaction along the metacarpals&#44; distal radius&#44; ulna&#44; tibia and fibula &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41; but not acro-osteolysis of the distal phalanges of the hands and feet&#46; Human immunodeficiency virus antibody test was negative&#46; Pharmacologic therapy with nonsteroidal anti-inflammatory drugs was effective in relieving pain from hypertrophic osteoarthropathy &#40;HOA&#41; during his hospital stay and after 3 months of follow-up&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Discussion</span><p id="par0015" class="elsevierStylePara elsevierViewall">HOA is a syndrome characterized by digital clubbing&#44; periostosis of tubular bones and noninflammatory arthritis of large joints&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a> Digital clubbing is characterized by an increase of the normal 160-degree angle between the nail bed and the proximal nail-fold &#40;Lovibond&#39;s angle&#41;&#46; In clubbing&#44; this angle exceeds 180 degrees&#44; while in pseudoclubbing it is preserved&#46; Contrary to digital clubbing&#44; finger involvement is asymmetrical in the majority of the reported cases of pseudoclubbing&#44; and acro-osteolysis instead of an overgrowth of the phalangeal tufts seen in clubbing&#44; is the typical radiographic finding in pseudoclubbing&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">HOA is classified as either primary &#40;pachydermoperiostosis&#41; or secondary to pulmonary&#44; cardiac&#44; liver or gastrointestinal diseases characterized by arteriovenous shunt&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a> Pulmonary malignancies are the most common disorders associated with HOA &#40;80&#37;&#41;&#46; Chronic infections associated with cystic fibrosis&#44; subacute bacterial endocarditis&#44; acquired immunodeficiency syndrome and pulmonary tuberculosis are also associated with HOA&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> Our case illustrates the HOA as a rare late complication of pulmonary tuberculosis&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">The pathogenesis of HOA is unknown&#44; although an impaired lung function due to the exclusion of this organ from part of the circulation is common in most diseases associated with HOA&#46; It has been suggested that in hypoxic conditions&#44; megakaryocytes bypass the pulmonary circulation through arteriovenous shunts and directly reach the distal sites in the systemic circulation and interact with endothelial cells&#44; releasing growth factors&#44; such as vascular endothelial growth factor &#40;VEGF&#41;&#44; resulting in angiogenesis and thus digital clubbing&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;5&#8211;8</span></a> VEGF is a platelet-derived factor induced by hypoxia that produces vascular hyperplasia&#44; new bone formation&#44; edema&#44; and fibroblast&#47;osteoblast proliferation&#44; which are histological alterations of HOA&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">6&#8211;8</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Although the association of HOA with pulmonary tuberculosis has been rarely reported&#44;<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">9&#8211;12</span></a> physicians should consider HOA as a complication of non-neoplastic diseases&#44; such as pulmonary tuberculosis&#44; an endemic infection of the world&#39;s population&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Ethical disclosures</span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Protection of human and animal subjects</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Confidentiality of data</span><p id="par0045" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Right to privacy and informed consent</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors have obtained the written informed consent of the patients or subjects mentioned in the article&#46; The corresponding author is in possession of this document&#46;</p></span></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Conflicts of interest</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:4 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Discussion"
        ]
        1 => array:3 [
          "identificador" => "sec0015"
          "titulo" => "Ethical disclosures"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0020"
              "titulo" => "Protection of human and animal subjects"
            ]
            1 => array:2 [
              "identificador" => "sec0025"
              "titulo" => "Confidentiality of data"
            ]
            2 => array:2 [
              "identificador" => "sec0030"
              "titulo" => "Right to privacy and informed consent"
            ]
          ]
        ]
        2 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Conflicts of interest"
        ]
        3 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2014-05-09"
    "fechaAceptado" => "2014-10-16"
    "multimedia" => array:3 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 642
            "Ancho" => 1301
            "Tamanyo" => 105094
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Digital clubbing&#46; &#40;A&#41; Clubbed appearance of distal phalanges&#46; &#40;B&#41; Positive Schamroth&#39;s sign&#58; the normal diamond-shaped window created by placing the dorsal surfaces of terminal phalanges on opposing fingers together is obliterated in clubbing&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1029
            "Ancho" => 950
            "Tamanyo" => 112166
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Chest computer tomography scan showing cystic bronchiectasis and cavitation in the left lower and upper lobes&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 788
            "Ancho" => 1800
            "Tamanyo" => 162603
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Radiographs of wrists &#40;A and B&#41; and legs &#40;C&#41; showing periostosis &#40;arrows&#41; at metacarpals&#44; distal ends of the radius&#44; ulna&#44; tibia and fibula&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:12 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Digital clubbing and hypertrophic osteoarthropathy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46; Mart&#237;nez-Lav&#237;n"
                            1 => "C&#46; Pineda"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:5 [
                        "titulo" => "Rheumatology"
                        "paginaInicial" => "1701"
                        "paginaFinal" => "1705"
                        "edicion" => "5th ed&#46;"
                        "serieFecha" => "2011"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypertrophic osteoarthropathy&#58; what a rheumatologist should know about this uncommon condition"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Pineda"
                            1 => "M&#46; Mart&#237;nez-Lav&#237;n"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.rdc.2013.02.008"
                      "Revista" => array:6 [
                        "tituloSerie" => "Rheum Dis Clin North Am"
                        "fecha" => "2013"
                        "volumen" => "39"
                        "paginaInicial" => "383"
                        "paginaFinal" => "400"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23597970"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pseudoclubbing&#58; is it different from clubbing&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46;B&#46; Santiago"
                            1 => "I&#46; Lima"
                            2 => "A&#46;C&#46; Feitosa"
                            3 => "S&#46; Braz Ade"
                            4 => "L&#46;G&#46; Miranda"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.semarthrit.2008.01.018"
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Arthritis Rheum"
                        "fecha" => "2009"
                        "volumen" => "38"
                        "paginaInicial" => "452"
                        "paginaFinal" => "457"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18378280"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Periostitis and hypertrophic pulmonary <span class="elsevierStyleItalic">osteoarthropathy</span>&#58; report of 2 cases and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "Q&#46; Yao"
                            1 => "R&#46;D&#46; Altman"
                            2 => "E&#46; Brahn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.semarthrit.2008.07.001"
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Arthritis Rheum"
                        "fecha" => "2009"
                        "volumen" => "38"
                        "paginaInicial" => "458"
                        "paginaFinal" => "466"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18760449"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Megakaryocytes and platelet clumps as the cause of finger clubbing"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46;J&#46; Dickinson"
                            1 => "J&#46;F&#46; Martin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1987"
                        "volumen" => "2"
                        "paginaInicial" => "1434"
                        "paginaFinal" => "1435"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2574367"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Vascular endothelial growth factor &#40;VEGF&#41;-A and platelet-derived growth factor &#40;PDGF&#41; play a central role in the pathogenesis of digital clubbing"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Atkinson"
                            1 => "S&#46;B&#46; Fox"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/path.1565"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Pathol"
                        "fecha" => "2004"
                        "volumen" => "203"
                        "paginaInicial" => "721"
                        "paginaFinal" => "728"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15141388"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Exploring the cause of the most ancient clinical sign of medicine&#58; finger clubbing"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46; Martinez-Lavin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.semarthrit.2006.11.004"
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Arthritis Rheum"
                        "fecha" => "2007"
                        "volumen" => "36"
                        "paginaInicial" => "380"
                        "paginaFinal" => "385"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17276498"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Circulating vascular endothelial growth factor concentrations in a case of pulmonary hypertrophic osteoarthropathy&#46; Correlation with disease activity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Ol&#225;n"
                            1 => "M&#46; Portela"
                            2 => "C&#46; Navarro"
                            3 => "M&#46; Gaxiola"
                            4 => "L&#46;H&#46; Silveira"
                            5 => "V&#46; Ruiz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Rheumatol"
                        "fecha" => "2004"
                        "volumen" => "31"
                        "paginaInicial" => "614"
                        "paginaFinal" => "616"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14994415"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypertrophic osteoarthropathy in association with pulmonary tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "P&#46; Kelly"
                            1 => "P&#46; Manning"
                            2 => "P&#46; Corcoran"
                            3 => "L&#46; Clancy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1991"
                        "volumen" => "99"
                        "paginaInicial" => "769"
                        "paginaFinal" => "770"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1995244"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypertrophic osteoarthropathy associated with pulmonary tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "I&#46; Aissa"
                            1 => "A&#46; Messadi"
                            2 => "S&#46; Boudaya"
                            3 => "F&#46; El Mezni"
                            4 => "T&#46; Kilani"
                            5 => "H&#46; Gh&#233;dira"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.pneumo.2009.11.001"
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Pneumol Clin"
                        "fecha" => "2011"
                        "volumen" => "67"
                        "paginaInicial" => "101"
                        "paginaFinal" => "104"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21497724"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypertrophic osteoarthropathy in pulmonary tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;G&#46; Webb"
                            1 => "P&#46; Thomas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Tubercle"
                        "fecha" => "1986"
                        "volumen" => "67"
                        "paginaInicial" => "225"
                        "paginaFinal" => "228"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3775873"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypertrophic osteoarthropathy&#58; two unusual causes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46;V&#46; Barber"
                            1 => "R&#46; Lechler"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Postgrad Med J"
                        "fecha" => "1983"
                        "volumen" => "59"
                        "paginaInicial" => "254"
                        "paginaFinal" => "255"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6866884"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/1699258X/0000001100000004/v1_201506200144/S1699258X14002198/v1_201506200144/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "33641"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Reumatolog&#237;a Cl&#237;nica en im&#225;gnes"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/1699258X/0000001100000004/v1_201506200144/S1699258X14002198/v1_201506200144/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X14002198?idApp=UINPBA00004M"
]
Información del artículo
ISSN: 1699258X
Idioma original: Inglés
Datos actualizados diariamente
año/Mes Html Pdf Total
2024 Noviembre 7 16 23
2024 Octubre 45 38 83
2024 Septiembre 44 29 73
2024 Agosto 63 42 105
2024 Julio 61 43 104
2024 Junio 77 43 120
2024 Mayo 75 32 107
2024 Abril 71 38 109
2024 Marzo 88 42 130
2024 Febrero 82 33 115
2024 Enero 112 31 143
2023 Diciembre 68 31 99
2023 Noviembre 151 28 179
2023 Octubre 141 34 175
2023 Septiembre 131 35 166
2023 Agosto 156 16 172
2023 Julio 140 25 165
2023 Junio 111 15 126
2023 Mayo 138 26 164
2023 Abril 84 7 91
2023 Marzo 117 25 142
2023 Febrero 77 26 103
2023 Enero 84 23 107
2022 Diciembre 114 50 164
2022 Noviembre 122 22 144
2022 Octubre 123 31 154
2022 Septiembre 90 56 146
2022 Agosto 126 51 177
2022 Julio 121 48 169
2022 Junio 91 37 128
2022 Mayo 142 61 203
2022 Abril 97 58 155
2022 Marzo 116 60 176
2022 Febrero 134 43 177
2022 Enero 140 42 182
2021 Diciembre 94 45 139
2021 Noviembre 114 50 164
2021 Octubre 107 57 164
2021 Septiembre 119 41 160
2021 Agosto 147 50 197
2021 Julio 160 44 204
2021 Junio 120 51 171
2021 Mayo 111 43 154
2021 Abril 332 137 469
2021 Marzo 158 30 188
2021 Febrero 100 32 132
2021 Enero 75 22 97
2020 Diciembre 82 26 108
2020 Noviembre 92 27 119
2020 Octubre 113 22 135
2020 Septiembre 75 29 104
2020 Agosto 55 15 70
2020 Julio 70 25 95
2020 Junio 78 55 133
2020 Mayo 78 31 109
2020 Abril 74 51 125
2020 Marzo 62 27 89
2020 Febrero 78 29 107
2020 Enero 76 26 102
2019 Diciembre 73 27 100
2019 Noviembre 48 27 75
2019 Octubre 54 22 76
2019 Septiembre 33 31 64
2019 Agosto 70 16 86
2019 Julio 88 26 114
2019 Junio 90 19 109
2019 Mayo 102 108 210
2019 Abril 48 40 88
2019 Marzo 60 26 86
2019 Febrero 52 25 77
2019 Enero 73 28 101
2018 Diciembre 126 74 200
2018 Noviembre 120 17 137
2018 Octubre 105 16 121
2018 Septiembre 62 13 75
2018 Agosto 57 14 71
2018 Julio 23 10 33
2018 Mayo 2 3 5
2018 Abril 45 9 54
2018 Marzo 93 17 110
2018 Febrero 34 11 45
2018 Enero 20 8 28
2017 Diciembre 35 7 42
2017 Noviembre 32 7 39
2017 Octubre 30 9 39
2017 Septiembre 25 19 44
2017 Agosto 33 18 51
2017 Julio 33 18 51
2017 Junio 55 10 65
2017 Mayo 70 13 83
2017 Abril 36 5 41
2017 Marzo 51 15 66
2017 Febrero 95 14 109
2017 Enero 26 5 31
2016 Diciembre 54 9 63
2016 Noviembre 53 7 60
2016 Octubre 84 15 99
2016 Septiembre 112 16 128
2016 Agosto 18 12 30
2016 Julio 16 9 25
2015 Diciembre 2 0 2
2015 Noviembre 2 27 29
2015 Octubre 4 27 31
2015 Septiembre 2 0 2
2015 Agosto 6 64 70
2015 Julio 57 57 114
2015 Junio 51 37 88
Mostrar todo

Siga este enlace para acceder al texto completo del artículo

Idiomas
Reumatología Clínica
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?