Images in Clinical Rheumatology
Schwannomas mimicking rheumatologic conditions
Schwannomas imitando patologías reumatológicas
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"autores" => array:4 [ 0 => array:4 [ "nombre" => "Joana" "apellidos" => "Silva-Dinis" "email" => array:1 [ 0 => "joanadasilvadinis@gmail.com" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Ana" "apellidos" => "Valido" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "Joaquim" "apellidos" => "Polido-Pereira" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "Nikita" "apellidos" => "Khmelinskii" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Serviço de Reumatologia, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Centro Académico de Medicina de Lisboa, Lisboa, Portugal" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Unidade de Investigação em Reumatologia, Instituto de Medicina Molecular, Centro Académico de Medicina de Lisboa, Lisboa, Portugal" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Schwannomas imitando patologías reumatológicas" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1870 "Ancho" => 2500 "Tamanyo" => 332827 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Picture of an enlarging mass on the distal part of the anterior aspect of the forearm and wrist (A). Ultrasound (B) and T1-weighted MRI images (C–E) depict multiple well-defined gadolium-enhanced masses (*) originating from the cubital nerve (arrow) suggestive of cubital nerve schwannoma.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Schwannomas, also known as neurilemmomas or Schwann cell tumors, are benign tumors originating from Schwann cells of the peripheral nerve sheath, occurring more frequently along the brachial plexus and spinal nerves.<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">1–4</span></a> Despite being the most common tumors of the peripheral nerve sheath, they are rarely encountered and diagnosis is often delayed.<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">2,4</span></a> These entities can mimic rheumatologic conditions such as synovial cysts, bursitis or ganglions.</p><p id="par0010" class="elsevierStylePara elsevierViewall">A 36-year-old healthy woman (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>) presented with a five-year history of a slowly enlarging mass in the popliteal region, with no previous history of trauma. A mobile and solid mass was palpable at the popliteal region evocative of a Baker's cyst, although the Foucher's sign was not present on examination. The patient was referred for ultrasound-guided aspiration and corticosteroid infiltration. However, ultrasound (US) documented a 29.9<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>25.5<span class="elsevierStyleHsp" style=""></span>mm heterogeneous solid mass in the popliteal region, originating from the tibial nerve. Magnetic resonance imaging (MRI) showed a homogeneous low intensity in T1-weighted images and heterogeneous high intensity in T2-weighted images, suggestive of a tibial nerve schwannoma.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">A 47-year-old healthy male (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>) presented with a one-year history of an enlarging mass on the distal part of the anterior aspect of the forearm and wrist, with no associated trauma or inflammatory signs. The clinical diagnosis was of a synovial cyst and the patient was referred for US-guided aspiration. US identified well-defined masses (the biggest with 26<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>11<span class="elsevierStyleHsp" style=""></span>mm) originating from the cubital nerve. The diagnosis of cubital nerve schwannoma was confirmed by MRI, which documented 5 nodular masses originating from the cubital nerve.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Both patients were referred to but refused surgical excision of the tumors.</p><p id="par0025" class="elsevierStylePara elsevierViewall">These cases highlight the importance of considering schwannomas in the evaluation of patients with nodules suggestive of synovial cysts, both on physical examination and when performing US or US-guided techniques. In both cases, US was crucial for the correct diagnosis these entities.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflict of interests</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare no conflict of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflict of interests" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2019-10-19" "fechaAceptado" => "2020-01-08" "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1500 "Ancho" => 1476 "Tamanyo" => 231626 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Ultrasound (A, B) and MRI (C, D) images of the knee depicting a well-defined solid mass (*) localized in the popliteal region, originating from the tibial nerve (arrows), with a heterogeneous structure with low intensity MRI-signal on T1 sequences and high intensity on DP SPAIR (C) and T2 sequences (D).</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1870 "Ancho" => 2500 "Tamanyo" => 332827 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Picture of an enlarging mass on the distal part of the anterior aspect of the forearm and wrist (A). Ultrasound (B) and T1-weighted MRI images (C–E) depict multiple well-defined gadolium-enhanced masses (*) originating from the cubital nerve (arrow) suggestive of cubital nerve schwannoma.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:4 [ 0 => array:3 [ "identificador" => "bib0025" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tarsal tunnel syndrome caused by a Schwannoma of the posterior tibial nerve" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "K. Watanabe" 1 => "T. Fukuzawa" 2 => "K. Mitsui" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.18926/AMO/55667" "Revista" => array:6 [ "tituloSerie" => "Acta Med Okayama" "fecha" => "2018" "volumen" => "72" "paginaInicial" => "77" "paginaFinal" => "80" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29463943" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0030" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Schwannoma of the posterior tibial nerve" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "T. Judd" 1 => "T. Jones" 2 => "L. Thornberry" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.7547/0003-0538-104.5.539" "Revista" => array:6 [ "tituloSerie" => "J Am Podiatr Med Assoc" "fecha" => "2014" "volumen" => "104" "paginaInicial" => "539" "paginaFinal" => "543" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25275747" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0035" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Popliteal schwannoma mimicking baker cyst: an unusual case" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "E. Komurcu" 1 => "U.H. Golge" 2 => "B. Kaymaz" 3 => "N. Erdogan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/jscr/rjt066" "Revista" => array:3 [ "tituloSerie" => "J Surg Case Rep" "fecha" => "2013" "volumen" => "2013" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0040" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Management of extremity neurilemmomas: clinical series and literature review" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "C.-S. Lai" 1 => "I.-C. Chen" 2 => "H.-C. Lan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/SAP.0000000000000042" "Revista" => array:6 [ "tituloSerie" => "Ann Plast Surg" "fecha" => "2013" "volumen" => "71" "paginaInicial" => "S37" "paginaFinal" => "S42" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24284739" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/1699258X/0000001700000006/v1_202105200700/S1699258X20300188/v1_202105200700/en/main.assets" "Apartado" => array:4 [ "identificador" => "42683" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Reumatología clínica en imágenes" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/1699258X/0000001700000006/v1_202105200700/S1699258X20300188/v1_202105200700/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X20300188?idApp=UINPBA00004M" ]
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