array:24 [
  "pii" => "S2173574316300612"
  "issn" => "21735743"
  "doi" => "10.1016/j.reumae.2015.10.012"
  "estado" => "S300"
  "fechaPublicacion" => "2016-09-01"
  "aid" => "848"
  "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología"
  "copyrightAnyo" => "2015"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "sco"
  "cita" => "Reumatol Clin. 2016;12:292-3"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 1159
    "formatos" => array:3 [
      "EPUB" => 58
      "HTML" => 862
      "PDF" => 239
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S1699258X15001898"
      "issn" => "1699258X"
      "doi" => "10.1016/j.reuma.2015.10.014"
      "estado" => "S300"
      "fechaPublicacion" => "2016-09-01"
      "aid" => "848"
      "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología"
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "sco"
      "cita" => "Reumatol Clin. 2016;12:292-3"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 7949
        "formatos" => array:3 [
          "EPUB" => 175
          "HTML" => 6672
          "PDF" => 1102
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Reumatolog&#237;a cl&#237;nica en im&#225;genes</span>"
        "titulo" => "Enfermedad de Forestier-Rot&#233;s Querol&#58; progresi&#243;n radiol&#243;gica cervical y aparici&#243;n de disfagia"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "292"
            "paginaFinal" => "293"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Forestier-Rot&#233;s Querol disease&#58; Cervical radiological progression and onset of dysphagia"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0010"
            "etiqueta" => "Figura 2"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr2.jpeg"
                "Alto" => 2008
                "Ancho" => 1583
                "Tamanyo" => 166532
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Radiograf&#237;a cervical lateral &#40;2014&#41;&#46; Se aprecia un aumento del tama&#241;o de la osificaci&#243;n del ligamento anterior cervical con afectaci&#243;n global de la columna cervical &#40;1&#41; se puede observar como impronta &#40;&#42;&#41; hacia la v&#237;a a&#233;rea-digestiva&#46; Tambi&#233;n se observa una conservaci&#243;n relativa de la altura del espacio intervertebral &#40;2&#41;&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Miriam Garc&#237;a Garc&#237;a"
            "autores" => array:1 [
              0 => array:2 [
                "nombre" => "Miriam"
                "apellidos" => "Garc&#237;a Garc&#237;a"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2173574316300612"
          "doi" => "10.1016/j.reumae.2015.10.012"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574316300612?idApp=UINPBA00004M"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X15001898?idApp=UINPBA00004M"
      "url" => "/1699258X/0000001200000005/v1_201608210048/S1699258X15001898/v1_201608210048/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173574316300600"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2015.10.011"
    "estado" => "S300"
    "fechaPublicacion" => "2016-09-01"
    "aid" => "846"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "sco"
    "cita" => "Reumatol Clin. 2016;12:294-5"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1279
      "formatos" => array:3 [
        "EPUB" => 62
        "HTML" => 974
        "PDF" => 243
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Images in Clinical Rheumatology</span>"
      "titulo" => "Contained Chronic Rupture of Iliac Aneurysm Mimicking Sciatica"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "294"
          "paginaFinal" => "295"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Rotura cr&#243;nica contenida de aneurisma il&#237;aco simulando ci&#225;tica"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0015"
          "etiqueta" => "Fig&#46; 3"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr3.jpeg"
              "Alto" => 732
              "Ancho" => 951
              "Tamanyo" => 79438
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Computed tomography of pelvis&#46; Perforated right iliac bone &#40;arrowhead&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Noelia Alonso-G&#243;mez, Alejandro Gonz&#225;lez-Guti&#233;rrez, Pablo Molina L&#243;pez-Nava, Felipe S&#225;inz-Gonz&#225;lez"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Noelia"
              "apellidos" => "Alonso-G&#243;mez"
            ]
            1 => array:2 [
              "nombre" => "Alejandro"
              "apellidos" => "Gonz&#225;lez-Guti&#233;rrez"
            ]
            2 => array:2 [
              "nombre" => "Pablo"
              "apellidos" => "Molina L&#243;pez-Nava"
            ]
            3 => array:2 [
              "nombre" => "Felipe"
              "apellidos" => "S&#225;inz-Gonz&#225;lez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X15001874"
        "doi" => "10.1016/j.reuma.2015.10.012"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X15001874?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574316300600?idApp=UINPBA00004M"
    "url" => "/21735743/0000001200000005/v3_201704020032/S2173574316300600/v3_201704020032/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173574316300442"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2015.08.004"
    "estado" => "S300"
    "fechaPublicacion" => "2016-09-01"
    "aid" => "829"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Reumatol Clin. 2016;12:288-91"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1766
      "formatos" => array:3 [
        "EPUB" => 60
        "HTML" => 1223
        "PDF" => 483
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case Report</span>"
      "titulo" => "SAPHO Syndrome in the Differential Diagnosis of Metastasis"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "288"
          "paginaFinal" => "291"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "S&#237;ndrome de SAPHO como diagn&#243;stico diferencial de met&#225;stasis"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0020"
          "etiqueta" => "Fig&#46; 4"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr4.jpeg"
              "Alto" => 1320
              "Ancho" => 984
              "Tamanyo" => 122114
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Chest computed tomography&#46; Sclerosis in sternal manubrium&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Miguel &#193;ngel Berenguer Franc&#233;s, Alejandro Lafaurie Acevedo, Vicente Tormo Ferrero, Rafael Cardenal Macia, Francisco Jos&#233; Andreu Mart&#237;nez"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "Miguel &#193;ngel"
              "apellidos" => "Berenguer Franc&#233;s"
            ]
            1 => array:2 [
              "nombre" => "Alejandro"
              "apellidos" => "Lafaurie Acevedo"
            ]
            2 => array:2 [
              "nombre" => "Vicente"
              "apellidos" => "Tormo Ferrero"
            ]
            3 => array:2 [
              "nombre" => "Rafael"
              "apellidos" => "Cardenal Macia"
            ]
            4 => array:2 [
              "nombre" => "Francisco Jos&#233;"
              "apellidos" => "Andreu Mart&#237;nez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X15001552"
        "doi" => "10.1016/j.reuma.2015.08.010"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X15001552?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574316300442?idApp=UINPBA00004M"
    "url" => "/21735743/0000001200000005/v3_201704020032/S2173574316300442/v3_201704020032/en/main.assets"
  ]
  "en" => array:17 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Images in Clinical Rheumatology</span>"
    "titulo" => "Forestier-Rot&#233;s Querol Disease&#58; Cervical Radiological Progression and Onset of Dysphagia"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "292"
        "paginaFinal" => "293"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Miriam Garc&#237;a Garc&#237;a"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "Miriam"
            "apellidos" => "Garc&#237;a Garc&#237;a"
            "email" => array:1 [
              0 => "mairimg2&#64;gmail&#46;com"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Reumatolog&#237;a&#44; Hospital Universitario Nuestra Se&#241;ora de la Candelaria&#44; Santa Cruz de Tenerife&#44; Tenerife&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Enfermedad de Forestier-Rot&#233;s Querol&#58; progresi&#243;n radiol&#243;gica cervical y aparici&#243;n de disfagia"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 2008
            "Ancho" => 1583
            "Tamanyo" => 167173
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Radiography of lateral cervical spine &#40;2014&#41; showing an increase in the extent of ossification of anterior cervical ligament with overall involvement of the cervical spine &#40;1&#41;&#44; and a protuberance &#40;&#42;&#41; toward the aerodigestive tract&#46; A relative conservation of the height of the intervertebral disc space is also observed &#40;2&#41;&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The patient was a 68-year-old man with a personal history of Forestier-Rot&#233;s Querol disease&#44; hypertension&#44; type II diabetes mellitus&#44; hepatic steatosis and Haglund&#39;s disease in right foot&#46; He reported a worsening of the clinical signs and symptoms in cervical spine over the preceding year&#44; with continuous pain and progressive limitation for movements from side to side&#44; and no evidence of radiculopathy or myelopathy&#46; He also complained of dysphagia with solid food and&#44; to a lesser extent&#44; with liquids&#44; and had lost 15<span class="elsevierStyleHsp" style=""></span>kg over the preceding year&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">The involvement of cervical spine in this disease and the development of dysphagia has been documented previously&#46; However&#44; the purpose of presenting this case report is to show the radiological progression over a 5-year period in the same patient and its clinical impact&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">The radiographic changes in Forestier-Rot&#233;s Querol disease were described by Resnick in 1975&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">1</span></a> These criteria include the ossification of the anterior longitudinal ligament along the anterolateral surface of at least 4 contiguous vertebral bodies&#44; the preservation of disc height&#44; the absence of the vacuum phenomenon or marginal sclerosis in the vertebral bodies and the absence of ankylosis of the facet joints or changes in the sacroiliac joints&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">1</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">The assessment of the radiological changes in the cervical spine of this patient over a 5-year period revealed an increase in osteophyte size and in the ossification of anterior cervical ligament&#44; which affected several contiguous vertebrae &#40;<a class="elsevierStyleCrossRefs" href="#fig0005">Figs&#46; 1 and 2</a>&#41;&#46; This could explain an extrinsic cause of the dysphagia&#46; There are other radiological features of interest&#44; such as the relative preservation of the intervertebral disc space and the absence of involvement of the facet joints&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">Given the systemic signs&#44; the patient underwent gastroscopy and upper gastrointestinal series&#44; the results of which were normal&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Computed tomography of the cervical spine revealed ossification of anterior longitudinal ligament and anterior osteophytes&#44; with involvement basically in the upper cervical spine &#40;C2&#8211;C4&#41;&#44; which made forward motion of the aerodigestive tract more difficult&#46; There was no evidence of involvement of the facet joints&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">In conclusion&#44; dysphagia is a relatively common manifestation when the cervical anterior longitudinal ligament is affected&#46;<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">2&#44;3</span></a> In the differential diagnosis&#44; it is necessary to rule out both an intrinsic and an extrinsic component&#44; since the most frequent causes of dysphagia continue to be tumors&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">2</span></a> For treatment&#44; a conservative approach should be adopted &#40;analgesia&#44; rehabilitation&#44; suitable nutritional intake and monitoring for metabolic syndrome&#44; which is closely related to Forestier disease&#41;<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">4&#8211;7</span></a> and&#44; in more serious cases&#44; the compression produced by the osteophytes may require surgical intervention&#46;<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">3&#44;4</span></a> However&#44; there is a high percentage of recurrences following surgery&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">8</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Ethical Disclosures</span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Protection of human and animal subjects</span><p id="par0040" class="elsevierStylePara elsevierViewall">The author declares that no experiments were performed on humans or animals for this study&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Confidentiality of data</span><p id="par0045" class="elsevierStylePara elsevierViewall">The author declares that she has followed the protocols of her work center on the publication of patient data and that all the patients included in the study have been properly informed and have given their written consent to participate in said study&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Right to privacy and informed consent</span><p id="par0050" class="elsevierStylePara elsevierViewall">The author has obtained the written informed consent of the patients or subjects mentioned in the article&#46; The corresponding author is in possession of this document&#46;</p></span></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conflicts of Interest</span><p id="par0055" class="elsevierStylePara elsevierViewall">The author declares that she has no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:3 [
        0 => array:3 [
          "identificador" => "sec0005"
          "titulo" => "Ethical Disclosures"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0010"
              "titulo" => "Protection of human and animal subjects"
            ]
            1 => array:2 [
              "identificador" => "sec0015"
              "titulo" => "Confidentiality of data"
            ]
            2 => array:2 [
              "identificador" => "sec0020"
              "titulo" => "Right to privacy and informed consent"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Conflicts of Interest"
        ]
        2 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2015-06-04"
    "fechaAceptado" => "2015-10-30"
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Garc&#237;a Garc&#237;a M&#46; Enfermedad de Forestier-Rot&#233;s Querol&#58; progresi&#243;n radiol&#243;gica cervical y aparici&#243;n de disfagia&#46; Reumatol Clin&#46; 2016&#59;12&#58;292&#8211;293&#46;</p>"
      ]
    ]
    "multimedia" => array:2 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 2136
            "Ancho" => 1583
            "Tamanyo" => 208629
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Radiography of lateral cervical spine &#40;2009&#41; showing ossification of anterior cervical ligament&#44; which has a greater effect on the lower cervical segment &#40;1&#41;&#46; The intervertebral disc spaces &#40;2&#41; and facet joints are conserved &#40;3&#41;&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 2008
            "Ancho" => 1583
            "Tamanyo" => 167173
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Radiography of lateral cervical spine &#40;2014&#41; showing an increase in the extent of ossification of anterior cervical ligament with overall involvement of the cervical spine &#40;1&#41;&#44; and a protuberance &#40;&#42;&#41; toward the aerodigestive tract&#46; A relative conservation of the height of the intervertebral disc space is also observed &#40;2&#41;&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:8 [
            0 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diffuse idiopathic skeletal hyperostosis &#40;DISH&#41;&#58; Forestier&#39;s disease with extraspinal manifestations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46; Resnick"
                            1 => "S&#46;R&#46; Shaul"
                            2 => "J&#46;M&#46; Robins"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1148/15.3.513"
                      "Revista" => array:6 [
                        "tituloSerie" => "Radiology"
                        "fecha" => "1975"
                        "volumen" => "115"
                        "paginaInicial" => "513"
                        "paginaFinal" => "524"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1129458"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Enfermedad de Forestier-Rotes-Querol&#46; Osificaci&#243;n del ligamento longitudinal cervical anterior como causa de disfagia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L&#46; Alc&#225;zar"
                            1 => "P&#46; Jerez"
                            2 => "J&#46;C&#46; G&#243;mez-Angulo"
                            3 => "M&#46; Tamarit"
                            4 => "R&#46; Navarro"
                            5 => "J&#46;M&#46; Ortega"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurocirugia"
                        "fecha" => "2008"
                        "volumen" => "19"
                        "paginaInicial" => "350"
                        "paginaFinal" => "355"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18726046"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Department of orthopedic surgery&#46; Progressive dysphagia and neck pain due to diffuse idiopathic skeletal hyperostosis of the cervical spine&#58; a case report and literature review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46; Zhang"
                            1 => "D&#46; Ruan"
                            2 => "Q&#46; He"
                            3 => "T&#46; Wen"
                            4 => "P&#46; Yang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2147/CIA.S60146"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Interv Aging"
                        "fecha" => "2014"
                        "volumen" => "9"
                        "paginaInicial" => "553"
                        "paginaFinal" => "557"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24729695"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diffuse idiopathic skeletal hyperostosis&#58; a review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "F&#46;A&#46; Nascimento"
                            1 => "L&#46;A&#46; Gatto"
                            2 => "R&#46;O&#46; Lages"
                            3 => "H&#46;M&#46; Neto"
                            4 => "Z&#46; Demartini"
                            5 => "G&#46;L&#46; Koppe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4103/2152-7806.130675"
                      "Revista" => array:7 [
                        "tituloSerie" => "Surg Neurol Int"
                        "fecha" => "2014"
                        "volumen" => "5"
                        "numero" => "Suppl&#46; 3"
                        "paginaInicial" => "S122"
                        "paginaFinal" => "S125"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24843807"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Metabolic factors in diffuse idiopathic skeletal hyperostosis &#8211; a review of clinical data"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Pillai"
                            1 => "G&#46; Littlejohn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2174/1874312901408010116"
                      "Revista" => array:6 [
                        "tituloSerie" => "Open Rheumatol J"
                        "fecha" => "2014"
                        "volumen" => "8"
                        "paginaInicial" => "116"
                        "paginaFinal" => "128"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25598855"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Extraskeletal symptoms and comorbidities of diffuse idiopathic skeletal hyperostosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46; Terzi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.12998/wjcc.v2.i9.422"
                      "Revista" => array:7 [
                        "tituloSerie" => "World J Clin Cases"
                        "fecha" => "2014"
                        "volumen" => "2"
                        "paginaInicial" => "422"
                        "paginaFinal" => "425"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25232544"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673606694208"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diffuse idiopathic skeletal hyperostosis as a cause of dysphagia in a young patient with metabolic syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46; Agirman"
                            1 => "O&#46; Durmus"
                            2 => "T&#46; Ormeci"
                            3 => "B&#46; Teker"
                            4 => "E&#46; Cakar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.pmrj.2014.11.006"
                      "Revista" => array:6 [
                        "tituloSerie" => "PM R"
                        "fecha" => "2015"
                        "volumen" => "7"
                        "paginaInicial" => "451"
                        "paginaFinal" => "452"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25460208"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Postoperative radiotherapy in diffuse idiopathic skeletal hyperostosis&#58; prophylaxis of recurrence after resection of osteophytes from C3 to C5 in a case of dysphagia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "F&#46;P&#46; Proescholdt"
                            1 => "M&#46;M&#46; Markart"
                            2 => "W&#46;D&#46; Ertel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/jscr/rjt124"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Surg Case Rep"
                        "fecha" => "2014"
                        "volumen" => "2014"
                        "paginaInicial" => "rjt124"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24876327"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735743/0000001200000005/v3_201704020032/S2173574316300612/v3_201704020032/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "5795"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Images in Clinical Rheumatology"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735743/0000001200000005/v3_201704020032/S2173574316300612/v3_201704020032/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574316300612?idApp=UINPBA00004M"
]
Share
Journal Information
Vol. 12. Issue 5.
Pages 292-293 (September - October 2016)
Vol. 12. Issue 5.
Pages 292-293 (September - October 2016)
Images in Clinical Rheumatology
Full text access
Forestier-Rotés Querol Disease: Cervical Radiological Progression and Onset of Dysphagia
Enfermedad de Forestier-Rotés Querol: progresión radiológica cervical y aparición de disfagia
Visits
6289
Miriam García García
Servicio de Reumatología, Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Tenerife, Spain
This item has received
Article information
Full Text
Bibliography
Download PDF
Statistics
Figures (2)
Full Text

The patient was a 68-year-old man with a personal history of Forestier-Rotés Querol disease, hypertension, type II diabetes mellitus, hepatic steatosis and Haglund's disease in right foot. He reported a worsening of the clinical signs and symptoms in cervical spine over the preceding year, with continuous pain and progressive limitation for movements from side to side, and no evidence of radiculopathy or myelopathy. He also complained of dysphagia with solid food and, to a lesser extent, with liquids, and had lost 15kg over the preceding year.

The involvement of cervical spine in this disease and the development of dysphagia has been documented previously. However, the purpose of presenting this case report is to show the radiological progression over a 5-year period in the same patient and its clinical impact.

The radiographic changes in Forestier-Rotés Querol disease were described by Resnick in 1975.1 These criteria include the ossification of the anterior longitudinal ligament along the anterolateral surface of at least 4 contiguous vertebral bodies, the preservation of disc height, the absence of the vacuum phenomenon or marginal sclerosis in the vertebral bodies and the absence of ankylosis of the facet joints or changes in the sacroiliac joints.1

The assessment of the radiological changes in the cervical spine of this patient over a 5-year period revealed an increase in osteophyte size and in the ossification of anterior cervical ligament, which affected several contiguous vertebrae (Figs. 1 and 2). This could explain an extrinsic cause of the dysphagia. There are other radiological features of interest, such as the relative preservation of the intervertebral disc space and the absence of involvement of the facet joints.

Fig. 1.

Radiography of lateral cervical spine (2009) showing ossification of anterior cervical ligament, which has a greater effect on the lower cervical segment (1). The intervertebral disc spaces (2) and facet joints are conserved (3).

(0.2MB).
Fig. 2.

Radiography of lateral cervical spine (2014) showing an increase in the extent of ossification of anterior cervical ligament with overall involvement of the cervical spine (1), and a protuberance (*) toward the aerodigestive tract. A relative conservation of the height of the intervertebral disc space is also observed (2).

(0.16MB).

Given the systemic signs, the patient underwent gastroscopy and upper gastrointestinal series, the results of which were normal.

Computed tomography of the cervical spine revealed ossification of anterior longitudinal ligament and anterior osteophytes, with involvement basically in the upper cervical spine (C2–C4), which made forward motion of the aerodigestive tract more difficult. There was no evidence of involvement of the facet joints.

In conclusion, dysphagia is a relatively common manifestation when the cervical anterior longitudinal ligament is affected.2,3 In the differential diagnosis, it is necessary to rule out both an intrinsic and an extrinsic component, since the most frequent causes of dysphagia continue to be tumors.2 For treatment, a conservative approach should be adopted (analgesia, rehabilitation, suitable nutritional intake and monitoring for metabolic syndrome, which is closely related to Forestier disease)4–7 and, in more serious cases, the compression produced by the osteophytes may require surgical intervention.3,4 However, there is a high percentage of recurrences following surgery.8

Ethical DisclosuresProtection of human and animal subjects

The author declares that no experiments were performed on humans or animals for this study.

Confidentiality of data

The author declares that she has followed the protocols of her work center on the publication of patient data and that all the patients included in the study have been properly informed and have given their written consent to participate in said study.

Right to privacy and informed consent

The author has obtained the written informed consent of the patients or subjects mentioned in the article. The corresponding author is in possession of this document.

Conflicts of Interest

The author declares that she has no conflicts of interest.

References
[1]
D. Resnick, S.R. Shaul, J.M. Robins.
Diffuse idiopathic skeletal hyperostosis (DISH): Forestier's disease with extraspinal manifestations.
Radiology, 115 (1975), pp. 513-524
[2]
L. Alcázar, P. Jerez, J.C. Gómez-Angulo, M. Tamarit, R. Navarro, J.M. Ortega, et al.
Enfermedad de Forestier-Rotes-Querol. Osificación del ligamento longitudinal cervical anterior como causa de disfagia.
Neurocirugia, 19 (2008), pp. 350-355
[3]
C. Zhang, D. Ruan, Q. He, T. Wen, P. Yang.
Department of orthopedic surgery. Progressive dysphagia and neck pain due to diffuse idiopathic skeletal hyperostosis of the cervical spine: a case report and literature review.
Clin Interv Aging, 9 (2014), pp. 553-557
[4]
F.A. Nascimento, L.A. Gatto, R.O. Lages, H.M. Neto, Z. Demartini, G.L. Koppe.
Diffuse idiopathic skeletal hyperostosis: a review.
Surg Neurol Int, 5 (2014), pp. S122-S125
[5]
S. Pillai, G. Littlejohn.
Metabolic factors in diffuse idiopathic skeletal hyperostosis – a review of clinical data.
Open Rheumatol J, 8 (2014), pp. 116-128
[6]
R. Terzi.
Extraskeletal symptoms and comorbidities of diffuse idiopathic skeletal hyperostosis.
World J Clin Cases, 2 (2014), pp. 422-425
[7]
M. Agirman, O. Durmus, T. Ormeci, B. Teker, E. Cakar.
Diffuse idiopathic skeletal hyperostosis as a cause of dysphagia in a young patient with metabolic syndrome.
[8]
F.P. Proescholdt, M.M. Markart, W.D. Ertel.
Postoperative radiotherapy in diffuse idiopathic skeletal hyperostosis: prophylaxis of recurrence after resection of osteophytes from C3 to C5 in a case of dysphagia.
J Surg Case Rep, 2014 (2014), pp. rjt124

Please cite this article as: García García M. Enfermedad de Forestier-Rotés Querol: progresión radiológica cervical y aparición de disfagia. Reumatol Clin. 2016;12:292–293.

Copyright © 2015. Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología
Download PDF
Idiomas
Reumatología Clínica (English Edition)
Article options
Tools
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?