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Vol. 13. Issue 2.
Pages 107-109 (March - April 2017)
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Vol. 13. Issue 2.
Pages 107-109 (March - April 2017)
Case report
DOI: 10.1016/j.reumae.2016.02.008
Multiple Vertebral Fractures in Young Man as First Manifestation of Systemic Mastocytosis
Fracturas vertebrales múltiples en varón joven como primera manifestación de una mastocitosis sistémica
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Carmen Carrasco Cuberoa,
Corresponding author
, Eugenio Chamizo Carmonab
a Servicio de Reumatología, Complejo Hospitalario Universitario de Badajoz, Hospital Perpetuo Socorro, Badajoz, Spain
b Servicio de Reumatología, Hospital de Mérida, Mérida, Spain
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Table 1.
Abstract

Systemic mastocytosis (SM) is a clonal disease of mast cell progenitors from the bone marrow. The clinical picture varies from asymptomatic forms (indolent) to a highly aggressive form with a very short (mast cell leukemia) survival. Between 28 and 34% of patients with SM are related to bone condition at the time of diagnosis and 16% have symptomatic fractures. The presentation of SM as clinical vertebral fractures in young men is rare. Here, we describe a case of established osteoporosis as the only manifestation of SM.

Keywords:
Vertebral fractures
Male osteoporosis
Systemic mastocytosis
Resumen

La mastocitosis sistémica (MS) es una enfermedad clonal de los progenitores mastocíticos de la médula ósea. El cuadro clínico varía desde una forma asintomática (indolente) hasta una forma altamente agresiva con una supervivencia muy corta (leucemia de mastocitos). Un 28-34% de los pacientes con MS tiene síntomas relacionados con la afección ósea en el momento del diagnóstico y el 16% fracturas. La presentación de MS como fracturas vertebrales clínicas en varones jóvenes no es frecuente. A continuación describimos un caso de osteoporosis establecida como única manifestación de MS.

Palabras clave:
Fracturas vertebrales
Osteoporosis del varón
Mastocitosis sistémica

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