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chondrosarcoma and osteochondroma with malignant degeneration&#46; It was finally decided that ultrasound-guided percutaneous biopsy be performed&#44; the result of which was mesenchymal tumour without signs of malignancy and final diagnosis of myositis ossificans was made&#46; Rest&#44; anti-inflammatory treatment and physiotherapy were recommended as treatment&#46; Three months later the patient showed clinical signs of improvement and a reduction in pain&#44; with complete flexion and extension at 120&#176;&#46; Plain radiological control &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>A and B&#41; and noncontrast CT imaging &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41; revealed a calcified mass&#44; compatible with the anatomopathological diagnosis&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Didactic Message</span><p id="par0010" class="elsevierStylePara elsevierViewall">Confined myositis ossificans is a rare entity of uncertain aetiopathogenesis&#44; characterised by a cellular metaplasia of connective tissue induced by trauma&#46;<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">1&#8211;3</span></a> Examination highlights a hardened tumour which is indistinguishable from other tumour lesions&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">1</span></a> Its main problem arises from generally being confused with malignant &#40;and particularly soft tissue sarcoma&#41; and infectious &#40;osteomyelitis&#41; processes&#46;<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">1&#44;2</span></a> It is important to be familiar with the morphological&#8211;functional characteristics of this lesion&#44; which evolve at different stages&#44; the acute phase producing an inflammatory reaction with a clinical and radiological pattern that is difficult to distinguish from aggressive conditions&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">2</span></a> The creation of an exhaustive medical history is essential &#40;possible trauma&#44; repeated aggressions&#44; burns&#44; prolonged immobilisation&#44; traumatic paralysis&#41; and an anatomopathologic study to rule out myositis ossificans which is a benign pathology treated in a conservative manner&#46;<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">1&#8211;4</span></a></p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Authorship</span><p id="par0015" class="elsevierStylePara elsevierViewall"><ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">1&#46;</span><p id="par0020" class="elsevierStylePara elsevierViewall">Manuscript conception and design&#58; Elena Espinosa Mu&#241;oz&#46;</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">2&#46;</span><p id="par0025" class="elsevierStylePara elsevierViewall">Data collection&#58; Elena Espinosa Mu&#241;oz&#46;</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">3&#46;</span><p id="par0030" class="elsevierStylePara elsevierViewall">Data analysis and interpretation&#58; Elena Espinosa Mu&#241;oz&#44; Diego Ram&#237;rez Oca&#241;a&#44; Ana Mar&#237;a Mart&#237;n Garc&#237;a and Carmen Puentes Zarzuela&#46;</p></li><li class="elsevierStyleListItem" id="lsti0020"><span class="elsevierStyleLabel">4&#46;</span><p id="par0035" class="elsevierStylePara elsevierViewall">Manuscript redaction&#44; review&#44; and approval&#58; Elena Espinosa Mu&#241;oz&#44; Diego Ram&#237;rez Oca&#241;a&#44; Ana Mar&#237;a Mart&#237;n Garc&#237;a and Carmen Puentes Zarzuela&#46;</p></li></ul></p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Ethical Liabilities</span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Protection of people and animals</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare that for this research no experimentation has been carried out on human beings or animals&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Data confidentiality</span><p id="par0045" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Right to privacy and informed consent</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Conflict of Interests</span><p id="par0055" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
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Journal Information
Vol. 15. Issue 5.
Pages e57-e59 (September - October 2019)
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7127
Vol. 15. Issue 5.
Pages e57-e59 (September - October 2019)
Images in Clinical Rheumatology
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Myositis Ossificans in Elbow Mimicking Soft Tissue Sarcoma: Similar Clinical and Radiological Findings
Miositis osificante circunscrita en codo simulando un sarcoma de partes blandas: hallazgos clínico-radiológicos similares
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7127
Elena Espinosa Muñoz
Corresponding author
elenaespinosamunoz@gmail.com

Corresponding author.
, Diego Ramírez Ocaña, Ana María Martín García, Carmen Puentes Zarzuela
Unidad de Gestión Clínica de Medicina Nuclear, Hospital Regional Universitario de Málaga, Málaga, Spain
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We present the case of a 36 year old female, monitored for painful, progressive tumour in the anteromedial surface of the left elbow and functional deficit, of 2-month onset, which was resistant to analgesic treatment. She referred to a previous history of trauma, and had been diagnosed with fibrillar muscle rupture. Due to the persistence of symptoms, an out-patient MRI was performed which resulted in suspicion of soft tissue sarcoma and the patient was admitted to hospital for further study. Laboratory tests and a CT scan of the chest and abdomen were negative. A two phase bone scan (Fig. 1A and B), showed a heterogeneous uptake area in the anterior region of the left elbow with no relevant findings at any other level. Differential diagnosis was suggested as sarcoma of the soft tissue, chondrosarcoma and osteochondroma with malignant degeneration. It was finally decided that ultrasound-guided percutaneous biopsy be performed, the result of which was mesenchymal tumour without signs of malignancy and final diagnosis of myositis ossificans was made. Rest, anti-inflammatory treatment and physiotherapy were recommended as treatment. Three months later the patient showed clinical signs of improvement and a reduction in pain, with complete flexion and extension at 120°. Plain radiological control (Fig. 2A and B) and noncontrast CT imaging (Fig. 3) revealed a calcified mass, compatible with the anatomopathological diagnosis.

Fig. 1.

Two phase bone scan after the injection of 814MBq of 99mTc-hydroxy-biphosphonate. Static images after 10min (tissue phase [A]) and total body after 2h (bone phase [B]), where heterogeneous uptake may be observed of the radiotracer in anterior region of the left elbow (arrows).

(0.13MB).
Fig. 2.

Plain X-ray of left elbow in lateral projection (A) and anteroposterior (B) projection.

(0.19MB).
Fig. 3.

Noncontrast iv CT image of the left elbow. Both radiology studies show a calcified mass with a sclerotic surface not dependent upon on the radial cortex (arrows).

(0.02MB).
Didactic Message

Confined myositis ossificans is a rare entity of uncertain aetiopathogenesis, characterised by a cellular metaplasia of connective tissue induced by trauma.1–3 Examination highlights a hardened tumour which is indistinguishable from other tumour lesions.1 Its main problem arises from generally being confused with malignant (and particularly soft tissue sarcoma) and infectious (osteomyelitis) processes.1,2 It is important to be familiar with the morphological–functional characteristics of this lesion, which evolve at different stages, the acute phase producing an inflammatory reaction with a clinical and radiological pattern that is difficult to distinguish from aggressive conditions.2 The creation of an exhaustive medical history is essential (possible trauma, repeated aggressions, burns, prolonged immobilisation, traumatic paralysis) and an anatomopathologic study to rule out myositis ossificans which is a benign pathology treated in a conservative manner.1–4

Authorship

  • 1.

    Manuscript conception and design: Elena Espinosa Muñoz.

  • 2.

    Data collection: Elena Espinosa Muñoz.

  • 3.

    Data analysis and interpretation: Elena Espinosa Muñoz, Diego Ramírez Ocaña, Ana María Martín García and Carmen Puentes Zarzuela.

  • 4.

    Manuscript redaction, review, and approval: Elena Espinosa Muñoz, Diego Ramírez Ocaña, Ana María Martín García and Carmen Puentes Zarzuela.

Ethical LiabilitiesProtection of people and animals

The authors declare that for this research no experimentation has been carried out on human beings or animals.

Data confidentiality

The authors declare that no patient data appear in this article.

Right to privacy and informed consent

The authors declare that no patient data appear in this article.

Conflict of Interests

The authors have no conflicts of interest to declare.

References
[1]
A. Ríos Zambudio, J. Illana Moreno, A. Piñero Madrona, A. Parrilla Paricio.
Miositis osificante aguda.
Rev Clin Esp, 201 (2001), pp. 349-351
[2]
R. Dosdá, L. Martí-Bonmatí, J. Galant, L. Concepción.
Miositis osificante: evaluación mediante RM.
Radiologia, 41 (1999), pp. 211-214
[3]
S. Janeiro-Barrera, A. García-Sánchez, I. Molina-Barraguer, M. Ramos-Murguialday, M.A. Morey-Mas, J.I. Iriarte-Ortabe.
Miositis osificante traumática.
Rev Esp Cir Oral Maxilofac, 35 (2013), pp. 137-143
[4]
A. Pàmies, A. Samitier, J. Rodríguez-Fernández, R. Fontova.
Miositis osificante en los músculos del cuello.
Reumatol Clin, 11 (2015), pp. 182-183

Please cite this article as: Espinosa Muñoz E, Ramírez Ocaña D, Martín García AM, Puentes Zarzuela C. Miositis osificante circunscrita en codo simulando un sarcoma de partes blandas: hallazgos clínico-radiológicos similares. Reumatol Clin. 2019;15:e57–e59.

Copyright © 2017. Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología
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